Fredrik Swift
seniorrådgiver, PhD
Kontakt
Send e-post {model.translations.sendEmailTo} Fredrik.Swift@fhi.no
Avdeling
Fagområder
Jobber som administrativ leder i Senter for fruktbarhet og helse.
Utdannet biolog fra Universitetet i Poitiers, Frankrike.
PhD i hjertefysiologi og cellulære mekanismer for hjertesvikt fra Universitetet i Oslo.
Forskningsadministrativ erfaring fra Senter for hjertesviktforskning ved Oslo universitetssykehus/Universitetet i Oslo.
Tidligere lederassistent for Folkehelseinstituttets direktør, Camilla Stoltenberg.
Prosjekter og publikasjoner
- Jonas Skogestad, Jan Magnus Aronsen, Nils Tovsrud, Pimthanya Wanichawan, Karina Hougen, Mathis Korseberg Stokke, Cathrine Rein Carlson, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2019). Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes . Cardiovascular Research (CVR) s. 78-90. doi: 10.1093/cvr/cvz087
- Jan Magnus Aronsen, Jonas Skogestad, Alexandre Lewalle, William Edward Louch, Karina Hougen, Mathis Korseberg Stokke, Fredrik Swift, Steven Niederer, Nic P. Smith, Ole M Sejersted, Ivar Sjaastad, (2015). Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+ ,K+-ATPase α2 activity. Journal of Physiology s. 1509-1521. doi: 10.1113/jphysiol.2014.279893
- Jan Magnus Aronsen, Fredrik Swift, Ole M Sejersted, (2013). Cardiac sodium transport and excitation-contraction coupling. Journal of Molecular and Cellular Cardiology s. 11-19. doi: 10.1016/j.yjmcc.2013.06.003
- Mathis Korseberg Stokke, Nils Tovsrud, William Edward Louch, Leiv Øyehaug, Karina Hougen, Ole M Sejersted, Fredrik Swift, Ivar Sjaastad, (2013). I-CaL inhibition prevents arrhythmogenic Ca2+ waves caused by abnormal Ca2+ sensitivity of RyR or SR Ca2+ accumulation. Cardiovascular Research (CVR) s. 315-325. doi: 10.1093/cvr/cvt037
- Faye M. Drawnel, Dagmar Wachten, Jeffery D. Molkentin, Marjorie Maillet, Jan Magnus Aronsen, Fredrik Swift, Ivar Sjaastad, Ning Liu, Daniele Catalucci, Katsuhiko Mikoshiba, Chihiro Hisatsune, Hanneke Okkenhaug, Simon R. Andrews, Martin D. Bootman, HL Roderick, (2012). Mutual antagonism between IP3RII and miRNA-133a regulates calcium signals and cardiac hypertrophy. Journal of Cell Biology s. 783-798. doi: 10.1083/jcb.201111095
- Mathis Korseberg Stokke, Frederic Rivelsrud, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2012). Fra global til lokal - ny forståelse av den elektromekaniske koblingen i hjertet. Tidsskrift for Den norske legeforening (Tidsskriftet) s. 1457-1460. doi: 10.4045/tidsskr.11.1353
- Fredrik Swift, Clara Franzini-Armstrong, Leiv Øyehaug, Ulla Helene Enger, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, William Edward Louch, (2012). Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout. Proceedings of the National Academy of Sciences of the United States of America (PNAS) s. 3997-4001. doi: 10.1073/pnas.1120172109
- Cecilie Sjåland, Per Kristian Lunde, Fredrik Swift, Morten Munkvik, Madelene Ericsson, Marianne Lunde, Sigurd Boye, Geir Arve Christensen, Øyvind Ellingsen, Ole M Sejersted, Kristin Brevik Andersson, (2011). Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle. Journal of Physiology s. 6139-6155. doi: 10.1113/jphysiol.2011.211987
- Fredrik Swift, Nils Tovsrud, Ivar Sjaastad, Ole M Sejersted, Ernst Niggli, Marcel Egger, (2010). Functional coupling of alpha(2)-isoform Na+/K+-ATPase and Ca2+ extrusion through the Na+/Ca2+-exchanger in cardiomyocytes. Cell Calcium s. 54-60. doi: 10.1016/j.ceca.2010.06.006
- William Edward Louch, Ole M Sejersted, Fredrik Swift, (2010). There Goes the Neighborhood: Pathological Alterations in T-Tubule Morphology and Consequences for Cardiomyocyte Ca2+ Handling. Journal of Biomedicine and Biotechnology doi: 10.1155/2010/503906
- William Edward Louch, Karina Hougen, Halvor Kjeang Mørk, Fredrik Swift, Jan Magnus Aronsen, Ivar Sjaastad, Henrik Mikael Reims, Borghild Roald, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, (2010). Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout. Journal of Physiology s. 465-478. doi: 10.1113/jphysiol.2009.183517
- Fredrik Swift, Jon Arne Birkeland, Nils Tovsrud, Ulla Helene Enger, Jan Magnus Aronsen, William Edward Louch, Ivar Sjaastad, Ole M Sejersted, (2008). Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha(2)-isoform in heart failure. Cardiovascular Research (CVR) doi: 10.1093/cvr/cvn013
- Jon Arne Birkeland, Fredrik Swift, Nils Tovsrud, Ulla Helene Enger, Per Kristian Lunde, Eirik Qvigstad, Finn Olav Levy, Ole M Sejersted, Ivar Sjaastad, (2007). Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology s. H2367-H2376. doi: 10.1152/ajpheart.01375.2006
- Fredrik Swift, Nils Tovsrud, Ulla Helene Enger, Ivar Sjaastad, Ole M Sejersted, (2007). The Na+/K+ -ATPase a2 isoform regulates cardiac contractility in rat cardiomyocytes. Cardiovascular Research (CVR) s. 109-117. doi: 10.1016/j.cardiores.2007.03.017
- Trond Brattelid, E Qvigstad, Jan Magne Birkeland, Jon Arne Birkeland, F Swift, SVS Bekkevold, KA Krobert, Ole M. Sejersted, T Skomedal, JB Osnes, F. Levy, I Sjaastad, (2007). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology s. 767-779. doi: 10.1016/j.yjmcc.2007.08.019
- Fredrik Swift, Andreas Strømme Tævje, Bjørn Amundsen, Ole M Sejersted, Ivar Sjaastad, (2006). Slow diffusion of K+ in the T tubules of rat cardiomyocytes. Journal of applied physiology s. 1170-1176.
- Eirik Qvigstad, Ivar Sjaastad, Trond Brattelid, Caroline Nunn, Fredrik Swift, Jon Arne Birkeland, Kurt Allen Krobert, Geir Øystein Andersen, Ole M Sejersted, Jan-Bjørn Osnes, Finn Olav Levy, Tor Skomedal, (2005). Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart. Circulation Research s. 268-276.
- Fredrik Swift, Ivar Sjaastad, Ole M Sejersted, (2003). Er endret regulering av Na+ årsak til svekket kontraktilitet i myokard ved hjertesvikt?. Tidsskrift for Den norske legeforening (Tidsskriftet) s. 3036-3040.
- Ivar Sjaastad, Janny Bøkenes, Fredrik Swift, J. A. Wasserstrom, Ole M Sejersted, (2002). Normal contractions triggered by I(Ca,L) in ventricular myocytes from rats with postinfarction CHF. American Journal of Physiology. Heart and Circulatory Physiology s. H1225-H1236.
- Fredrik Swift, (2007). Restricted diffusion of ions regulates cardiac function.
- Jonas Skogestad, Jan Magnus Aronsen, Karina Hougen, Mathis Korseberg Stokke, Fredrik Swift, Ole M Sejersted, Ivar Sjaastad, (2013). Extracellular potassium regulates Ca2+ homeostasis through interaction between NCX and NKA.
- Jonas Skogestad, Jan Magnus Aronsen, Karina Hougen, Mathis Korseberg Stokke, Fredrik Swift, Ole M Sejersted, Ivar Sjaastad, (2012). Extracellular potassium regulates Ca2+ homeostasis through interaction between NCX and NKA.
- Fredrik Swift, Jan Magnus Aronsen, Mathis Korseberg Stokke, Karina Hougen, Marcel Egger, Llewelyn Roderick, Ole M Sejersted, Ivar Sjaastad, (2012). IP3 receptors in heart failure: arrhythmogenic troublemakers or SR calcium security valves?. Biophysical Journal s. 101a-101a.
- Fredrik Swift, Geir Arve Christensen, (2012). Calcium release units in heart failure: that's about the size of it. Cardiovascular Research (CVR) s. 397-398. doi: 10.1093/cvr/cvs241
- Jonas Skogestad, Jan Magnus Aronsen, Karina Hougen, Mathis Korseberg Stokke, Fredrik Swift, Ole M Sejersted, Ivar Sjaastad, (2012). Extracellular potassium regulates Ca2+ homeostasis through interaction between NCX and NKA.
- Fredrik Swift, Nils Tovsrud, Jan Magnus Aronsen, William Edward Louch, Mathis Korseberg Stokke, Ulla Helene Enger, Ivar Sjaastad, Ole M Sejersted, (2012). Crosstalk between NKA and NCX in a shared microdomain.
- Fredrik Swift, Clara Franzini-armstrong, Leiv Øyehaug, Ulla Helene Enger, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, William Edward Louch, (2011). Altered expression and localization of Na+/Ca2+ -exchanger to compensate for loss of SR Ca2+ ATPase.
- Nils Tovsrud, Mathis Korseberg Stokke, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2011). Stress-induced arrhythmias caused by reduction of ankyrin B.
- Mathis Korseberg Stokke, Nils Tovsrud, Fredrik Swift, William Edward Louch, Ole M Sejersted, Ivar Sjaastad, (2011). L-type Ca2+ current inhibition prevents arrhythmogenic SR Ca2+ release by reducing SR Ca2+ content.
- Fredrik Swift, Clara Franzini-Armstrong, Ulla Helene Enger, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, William Edward Louch, (2011). Remodeling of the sarcoplasmic reticulum and t-tubules in cardiomyocytes following conditional Serca2 knockout. Biophysical Journal s. 293a-293a.
- Fredrik Swift, Jan Magnus Aronsen, Mathis Korseberg Stokke, Karina Hougen, Ole M Sejersted, (2011). IP3 receptors in heart failure: Arrhythmogenic troublemakers or SR Ca2+ security valves?.
- William Edward Louch, Liren Li, Fredrik Swift, Mathis Korseberg Stokke, Steven A. Niederer, Samuel Sossalla, Lars S. Maier, Ivar Sjaastad, Geir Arve Christensen, Nic P. Smith, Ole M Sejersted, (2011). Causes and consequences of cardiomyocyte Na+ loading following SERCA2 knockout.
- Nils Tovsrud, Cathrine Rein Carlson, Pimthanya Wanichawan, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2010). Ankyrin B regulates Na/K-ATPase activity in mouse ventricular cardiomyocytes. European Journal of Heart Failure. Supplements s. S203-S203.
- Fredrik Swift, Ulla Helene Enger, Guro Five Jølle, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, William Edward Louch, (2010). T-tubule proliferation facilitates transsarcolemmal Ca2+ flux to compensate for declining SR function in Serca2 KO mice.
- Fredrik Swift, Nils Tovsrud, Ivar Sjaastad, Ernst Niggli, Ole M Sejersted, Marcel Egger, (2009). Blockade of Na/K-ATPase 2-isoform reduces the rate of Ca extrusion through the Na/Ca - exchanger. Acta Physiologica s. O25-O25.
- Nils Tovsrud, Cathrine Rein Carlson, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2009). The Ankyrin B- Na/K-ATPase interaction is important for normal Na/K-ATPase function. Acta Physiologica s. P7-P7.
- Nils Tovsrud, Cathrine Rein Carlson, Ivar Sjaastad, Ole M Sejersted, Fredrik Swift, (2009). The ankyrin B - Na/K-ATPase interaction is important for normal Na/K-ATPase function.
- Fredrik Swift, Nils Tovsrud, Ivar Sjaastad, Ernst Niggli, Ole M Sejersted, Marcel Egger, (2009). Blockade of Na+/K+ -ATPase a2-isoform reduces the rate of Ca2+ extrusion through the Na+/Ca2+ -exchanger.
- William Edward Louch, Karina Hougen, Jon magnus Aronsen, Halvor Kjeang Mørk, Fredrik Swift, Ivar Sjaastad, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, (2009). Compensation and decompensation following cardiac-specific knockout of SERCA2.
- William Edward Louch, Karina Hougen, Jan Magnus Aronsen, Halvor Kjeang Mørk, Fredrik Swift, Ivar Sjaastad, Kristin Brevik Andersson, Geir Arve Christensen, Ole M Sejersted, (2009). COMPENSATION AND DECOMPENSATION FOLLOWING CARDIAC-SPECIFIC KNOCKOUT OF SERCA2. Journal of Neurophysiology s. 313-313.
- Fredrik Swift, Nils Tovsrud, Ivar Sjaastad, E Niggli, Ole M Sejersted, M Egger, (2008). Blockade of Na+/K+-ATPase a2-isoform reduces the rate of Ca2+ extrusion through the Na+ Ca2+-exchanger.
- Fredrik Swift, Jon Arne Birkeland, Nils Tovsrud, Ulla Helene Enger, Jon magnus Aronsen, Ivar Sjaastad, Ole M Sejersted, (2007). Downregulation of the Na+/K+ -ATPase (NKA) a2-isoform in ventricular myocytes from rats with congestive heart failure.
- Trond Brattelid, Eirik Qvigstad, Jon Arne Birkeland, Fredrik Swift, SVS Bekkevold, Kurt Allen Krobert, Ole M Sejersted, Tor Skomedal, Jan-Bjørn Osnes, Finn Olav Levy, Ivar Sjaastad, (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology s. 944-945.
- Eirik Qvigstad, Ivar Sjaastad, Trond Brattelid, Caroline Nunn, Fredrik Swift, Jon Arne Birkeland, Kurt Allen Krobert, Geir Øystein Andersen, Ole M Sejersted, Jan-Bjørn Osnes, Finn Olav Levy, Tor Skomedal, (2006). Induction of functional serotonin 5-HT2A and 5-HT4 receptors in the acute failing cardiac ventricle. Journal of Pharmacological Sciences (JPS) s. 73-73.
- Trond Brattelid, Eirik Qvigstad, Jon Arne Birkeland, Fredrik Swift, Silje Veslemøy Bekkevold, Kurt Allen Krobert, Ole M Sejersted, Tor Skomedal, Jan-Bjørn Osnes, Finn Olav Levy, Ivar Sjaastad, (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Pharmacological Sciences (JPS) s. 74-74.
- Fredrik Swift, Ulla Helene Enger, Ivar Sjaastad, Ole M Sejersted, (2006). The role of sodium in the heart - subcellular regulation controlds contractility.
- Fredrik Swift, William Edward Louch, Jon Arne Birkeland, M. Thomas, Ivar Sjaastad, Ole M Sejersted, (2006). Reduced t-tubule density and less synchronous Ca2+ release in cardiomyocytes from rats with congestive heart failure.
- Fredrik Swift, Jon Arne Birkeland, Marion J. Thomas, Ivar Sjaastad, Ole M Sejersted, (2006). Reduced t-tubule density and less synchronous Ca2+ release in cardiomyocytes from rats with congestive heart failure.
- Jon Arne Birkeland, Fredrik Swift, Nils Tovsrud, G.R. Ferrier, Finn Olav Levy, Ole M Sejersted, (2005). Induction of a 5-HT receptor-mediated inotropic response to serotonin in failing ventricular cardiomyocytes. Journal of Molecular and Cellular Cardiology
- Fredrik Swift, Nils Tovsrud, Ulla Helene Enger, Ivar Sjaastad, Ole M Sejersted, (2005). Subcellular distribution of the Na+/K+ -pump (NKA) isoforms in rat ventricular myocytes.