Prosjekter og publikasjoner
- Colin Hemez, Fabrizio Clarelli, Adam C. Palmer, Christina Bleis, Sören Abel, Leonid Chindelevitch, Theodore Cohen, Pia Abel zur Wiesch, (2022). Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations. Computational and Structural Biotechnology Journal s. 4688-4703. doi: 10.1016/j.csbj.2022.08.030
- Aaron Nicholas Gillman, Anel Mahmutovic, Pia Abel zur Wiesch, Sören Abel, (2021). The Infectious Dose Shapes Vibrio Cholerae Within-Host Dynamics. mSystems s. 1-19. doi: 10.1128/mSystems.00659-21
- Aaron Nicholas Gillman, Alexandra Helleux, Sören Abel, (2021). A single step three-strain in vivo Gateway reaction. Plasmid doi: 10.1016/j.plasmid.2021.102608
- Anel Mahmutovic, Pia Abel zur Wiesch, Sören Abel, (2020). Selection or drift: the population biology underlying transposon insertion sequencing experiments.. Computational and Structural Biotechnology Journal s. 791-804. doi: 10.1016/j.csbj.2020.03.021
- Fabrizio Clarelli, Adam Palmer, Bhupender Singh, Merete Storflor, Silje Lauksund, Ted Cohen, Sören Abel, Pia Abel zur Wiesch, (2020). Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones. PLoS Computational Biology doi: 10.1371/journal.pcbi.1008106
- Alyson R. Warr, Troy P. Hubbard, Diana Munera, Carlos J. Blondel, Pia Abel zur Wiesch, Sören Abel, Xiaoxue Wang, Brigid M. Davis, Matthew K. Waldor, (2019). Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization. PLoS Pathogens s. 1-33. doi: 10.1371/journal.ppat.1007652
- Antal Martinecz, Fabrizio Clarelli, Sören Abel, Pia Abel zur Wiesch, (2019). Reaction Kinetic Models of Antibiotic Heteroresistance. International Journal of Molecular Sciences doi: 10.3390/ijms20163965
- Ting Zhang, Sören Abel, Pia Abel zur Wiesch, Jumpei Sasabe, Brigid M. Davis, Darren E. Higgins, Matthew K. Waldor, (2017). Deciphering the landscape of host barriers to Listeria monocytogenes infection . Proceedings of the National Academy of Sciences of the United States of America s. 6334-6339. doi: 10.1073/pnas.1702077114
- Troy Hubbard, Michael C Chao, Sören Abel, Carlos J Blondel, Pia Abel zur Wiesch, Xiaohui Zhou, Brigid M. Davis, Matthew K. Waldor, (2016). Genetic analysis of vibrio parahaemolyticus intestinal colonization. Proceedings of the National Academy of Sciences of the United States of America s. 6283-6288. doi: 10.1073/pnas.1601718113
- Michael C Chao, Sören Abel, Brigid M. Davis, Matthew K. Waldor, (2016). The design and analysis of transposon insertion sequencing experiments. Nature Reviews Microbiology s. 119-128. doi: 10.1038/nrmicro.2015.7
- Stavroula K Hatzios, Sören Abel, Julianne Martell, Troy Hubbard, Jumpei Sasabe, Diana Munera, Lars Clark, Daniel A Bachovchin, F Qadri, Edward T Ryan, Brigid M. Davis, Eranthie Weerapana, Matthew K. Waldor, (2016). Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nature Chemical Biology s. 268-274. doi: 10.1038/nchembio.2025
- Sören Abel, Pia Karoline Abel-Zur Wiesch Genannt Hülsho, Hsiao-Han Chang, Brigid M. Davis, Marc Lipstich, Matthew K. Waldor, (2015). Sequence tag-based analysis of microbial population dynamics. Nature Methods s. 223-226. doi: 10.1038/nmeth.3253
- Sören Abel, Matthew K. Waldor, (2015). Infant rabbit model for diarrheal diseases. Current Protocols in Microbiology s. 6A.6.1-6A.6.15. doi: 10.1002/9780471729259.mc06a06s38
- Christian Lori, Shogo Ozaki, Samuel Steiner, Raphael Böhm, Sören Abel, Badri Nath Dubey, Tilman Schirmer, Sebastian Hiller, Urs Jenal, (2015). Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication. Nature s. 236-239. doi: 10.1038/nature14473
- Sören Abel, Pia Schulz Zur Wiesch, Brigid M. Davis, Matthew K. Waldor, (2015). Analysis of Bottlenecks in Experimental Models of Infection. PLoS Pathogens doi: 10.1371/journal.ppat.1004823
- Pia Abel zur Wiesch, Sören Abel, Spyridon Gkotzis, Paolo Ocampo, Jan Engelstädter, Trevor Hinkley, Carsten Magnus, Matthew K. Waldor, Klas Udekwu, Ted Cohen, (2015). Classic reaction kinetics can explain complex patterns of antibiotic action. Science Translational Medicine doi: 10.1126/scitranslmed.aaa8760
- Justin Pritchard, Michael C Chao, Sören Abel, Brigid M. Davis, Catherine Baranowski, Yanjia Zhang, Eric J Rubin, Matthew K. Waldor, (2014). ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing. PLoS Genetics doi: 10.1371/journal.pgen.1004782
- Pia Karoline Abel-Zur Wiesch Genannt Hülsho, Roger D. Kouyos, Sören Abel, Wolfgang Viechtbauer, Sebastian Bonhoeffer, (2014). Cycling empirical antibiotic therapy in hospitals: meta-analysis and models. PLoS Pathogens doi: 10.1371/journal.ppat.1004225
- Coralie Fumeaux, Sunish Radhakrishnan, Silvia Ardissone, Laurance Theraulaz, Antonio Frandi, Daniel Martins, Jutta Nesper, Sören Abel, Urs Jenal, Patrick Viollier, (2014). Cell cycle transition from S-phase to G1 in Caulobacter is mediated by ancestral virulence regulators. Nature Communications doi: 10.1038/ncomms5081
- Sören Abel, Tabitha Bucher, Micael Nicollier, Isabelle Hug, Volkhard Kaever, Pia Karoline Abel-Zur Wiesch Genannt Hülsho, Urs Jenal, (2013). Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle. PLoS Genetics doi: 10.1371/journal.pgen.1003744
- Sören Abel, Peter Chien, Paul Wassmann, Tilman Schirmer, Volkhard Kaever, Michael Laub, Tania Baker, Urs Jenal, (2011). Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks. Molecular Cell s. 550-560. doi: 10.1016/j.molcel.2011.07.018
- Andreas Diepold, Marlise Amstutz, Sören Abel, Isabel Sorg, Urs Jenal, Guy Cornelis, (2010). Deciphering the assembly of the Yersinia type III secretion injectisome. EMBO Journal s. 1928-1949. doi: 10.1038/emboj.2010.84
- Anna Duerig, Sören Abel, Marc Folcher, Micael Nicollier, Torsten Schwede, Nicolas Amiot, Bernd Giese, Urs Jenal, (2009). Second messenger-mediated spatiotemporal control of protein degradation regulates bacterial cell cycle progression. Genes & Development s. 93-104. doi: 10.1101/gad.502409
- Ralf Paul, Tina Jaeger, Sören Abel, Irene Wiederkehr, Marc Folcher, Emanuele Biondi, Michael Laub, Urs Jenal, (2008). Allosteric regulation of histidine kinases by their cognate response regulator determines cell fate. Cell s. 452-461. doi: 10.1016/j.cell.2008.02.045
- Ralf Paul, Sören Abel, Paul Wassmann, Andreas Beck, Heiko Heerklotz, Urs Jenal, (2007). Activation of the diguanylate cyclase PleD by phosphorylation-mediated dimerization. Journal of Biological Chemistry s. 29170-29177. doi: 10.1074/jbc.M704702200
- Sören Abel, Christian Hundhausen, Rolf Mentlein, Alexander Schulte, Theo Berkhout, Neil Broadway, Dieter H. Hartmann, Radek Sedlacek, Sebastian Dietrich, Barbara Muetze, Bjoern Schuster, Karl-Josef Kallen, Paul Saftig, Stefan Rose-John, Andreas Ludwig, (2004). The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10. Journal of Immunology s. 6362-6372. doi: 10.4049/jimmunol.172.10.6362
- Øyvind Myrvoll Lorentzen, Sören Abel, Pål Jarle Johnsen, (2022). Evolution of Vibrio cholerae biofilms.
- Anel Mahmutovic, Aaron Nicholas Gillman, Silje Lauksund, Natasha-Anne Robson Moe, Aimé Manzi, Merete Storflor, Pia Karoline Abel-Zur Wiesch Genannt Hülsho, Sören Abel, (2021). RESTAMP – Rate estimates by sequence-tag analysis of microbial populations. Computational and Structural Biotechnology Journal doi: 10.1016/j.csbj.2021.01.017
- Vidar Sørum, Anna Sollied Møller, Pål Jarle Johnsen, Ørjan Samuelsen, Sören Abel, Nicole L. Podnecky, (2019). Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains.
- Vidar Sørum, Anna Sollied Møller, Sören Abel, Ørjan Samuelsen, Nicole L. Podnecky, Pål Jarle Johnsen, (2019). Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains.
- Sebastian Andres Acuña Maldonado, Ida Sundvor Opstad, Luis Enrique Villegas Hernandez, Mona Nystad, Milton O Aguilera, Merete Storflor, Cristina Ionica Øie, Sören Abel, Åsa birna Birgisdottir, Trine Kalstad, Deanna Wolfson, Jean-Claude Tinguely, Truls Myrmel, Peter Anthony McCourt, Terje Johansen, Balpreet Singh Ahluwalia, Krishna Agarwal, (2019). Fluorescence Nanoscopy Using Multiple Signal Classiflcation Algorithm (MUSICAL): From Electromagnetics Inverse Scattering Problem to Optics Inverse Source Problem.
- Vidar Sørum, Emma Lu Øynes, Anna Møller, Nicole L. Podnecky, Sören Abel, Ørjan Samuelsen, Pål Jarle Johnsen, (2019). Evolutionary stability of collateral susceptibility networks in clinical Escherichia coli strains.
- Sören Abel, (2018). The within host spread of Vibrio cholerae.
- Sören Abel, (2018). The within host spread of Vibrio cholerae.
- Sören Abel, (2018). The within host spread of Vibrio cholerae.
- Fabrizio Clarelli, Bhupender Singh, Adam Palmer, Sören Abel, Ted Cohen, Pia Abel zur Wiesch, (2018). Quantitatively predicting antibiotic susceptibility from biochemical parameters: implications for antibiotic development and preventing resistance.
- Krishna Agarwal, Ida Sundvor Opstad, Jean-Claude Tinguely, Sören Abel, Trine Kalstad, Åsa birna Birgisdottir, Truls Myrmel, Balpreet Singh Ahluwalia, (2018). High-Speed, Multi-Color Live Cell Nanoscopy using MUSICAL.
- Sören Abel, (2018). The within host spread of Vibrio cholerae.
- Sören Abel, Anel Mahmutovic, Aaron Nicholas Gillman, Aime Manzi, Natasha-Anne Robson Moe, Silje Lauksund, Øyvind Lorentzen, Elizabeth Aarag, Julia Maria Kloos, Kristin Hegstad, Pauline Cavanagh, Christina Bleis, Merete Storflor, (2018). How to blast a biofilm.
- Fabrizio Clarelli, Bhupender Singh, Ted Cohen, Adam Palmer, Leonid Chindelevitch, Sören Abel, Pia Abel zur Wiesch, (2018). Using models to understand how molecular mechanisms of resistance affect the risk of acquired drug resistance during treatment.
- Fabrizio Clarelli, Ted Cohen, Sören Abel, Bhupender Singh, Adam Palmer, Leonid Chindelevitch, Pia Abel zur Wiesch, (2018). How molecular mechanisms of resistance affect resistance evolution.
- Merete Storflor, Armin Schniers, Terkel Hansen, Sören Abel, (2017). Quantifying c-di-GMP during infections on a single cell level.
- Christina Bleis, Sören Abel, (2017). Determining the cholerae acid tolerance genes by transposon insertion sequencing.
- Aaron Nicholas Gillman, Bhupender Singh, Sören Abel, (2017). Population Dynamics of V. cholerae.
- Fabrizio Clarelli, Leonid Chindelevitch, Bhupender Singh, Ted Cohen, Sören Abel, Pia Abel zur Wiesch, (2017). Using models to understand how molecular mechanisms of resistance affect the risk of acquired drug resistance during treatment.
- Ida Sundvor Opstad, Krishna Agarwal, Sören Abel, Balpreet Singh Ahluwalia, (2017). Multi-color nanoscopy of live-cell processes in E. Coli bacteria using MUSICAL.