Fagområder
Immunologi, Molekylærbiologi, Laboratorieforskning, Toksikologi, Dataanalyse, Kreftbiologi
Faglig bakgrunn
Lege; PhD i kreftimmunologi og inflammasjon; Postdok i immunreseptorbiologi og avanserte forskningsteknikker
Prosjekter og publikasjoner
- Philippe Paul Auguste Robert, Rahmad Akbar, Robert Frank, Milena Pavlović, Michael Widrich, Igor Snapkov, Andrei Slabodkin, Maria Chernigovskaya, Lonneke Scheffer, Eva Smorodina, Puneet Rawat, Brij Bhushan Mehta, Mai Ha Vu, Ingvild Frøberg Mathisen, Aurél Prósz, Krzysztof Abram, Alex Olar, Enkelejda Miho, Dag Trygve Truslew Haug, Fridtjof Lund-Johansen, Sepp Hochreiter, Ingrid Hobæk Haff, Günter Klambauer, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2022). Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction. Nature computational science s. 845-865. doi: 10.1038/s43588-022-00372-4
- Rahmad Akbar, Philippe Paul Auguste Robert, Cédric R. Weber, Michael Widrich, Robert Frank, Milena Pavlovic, Lonneke Scheffer, Maria Chernigovskaia, Igor Snapkow, Andrei Slabodkin, Brij Bhushan Mehta, Enkelejda Miho, Fridtjof Lund-Johansen, Jan Terje Andersen, Sepp Hochreiter, Ingrid Hobæk Haff, Günter Klambauer, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2022). In silico proof of principle of machine learning-based antibody design at unconstrained scale. mAbs s. 1-18. doi: 10.1080/19420862.2022.2031482
- Andrei Slabodkin, Maria Chernigovskaia, Ivana Mikocziova, Rahmad Akbar, Lonneke Scheffer, Milena Pavlović, Habib Bashour, Igor Snapkov, Brij Bhushan Mehta, Cédric R. Weber, Jose Gutierrez-Marcos, Ludvig Magne Sollid, Ingrid Hobæk Haff, Geir Kjetil Ferkingstad Sandve, Philippe Paul Auguste Robert, Victor Greiff, (2021). Individualized VDJ recombination predisposes the available Ig sequence space. Genome Research s. 2209-2225. doi: 10.1101/gr.275373.121
- Milena Pavlović, Lonneke Scheffer, Keshav Motwani, Chakravarthi Kanduri, Radmila Kompova, Nikolay Aleksandrov Vazov, Knut Waagan, Fabian Leonardo Martinez Bernal, Alexandre Almeida Costa, Brian Corrie, Rahmad Akbar, Ghadi S. Al Hajj, Gabriel Balaban, Todd M. Brusko, Mariia Chernigovskaia, Scott Christley, Lindsay G. Cowell, Robert Frank, Ivar Grytten, Sveinung Gundersen, Ingrid Hobæk Haff, Eivind Hovig, Ping-Han Hsieh, Günter Klambauer, Marieke L. Kuijjer, Christin Lund-Andersen, Antonio Martini, Thomas Minotto, Johan Pensar, Knut Dagestad Rand, Enrico Riccardi, Philippe Paul Auguste Robert, Artur Rocha, Andrei Slabodkin, Igor Snapkov, Ludvig Magne Sollid, Dmytro Titov, Cédric R. Weber, Michael Widrich, Gur Yaari, Victor Greiff, Geir Kjetil Ferkingstad Sandve, (2021). The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires. Nature Machine Intelligence s. 936-944. doi: 10.1038/s42256-021-00413-z
- Igor Snapkov, Maria Chernigovskaia, Pavel Sinitcyn, Quy Khang Le, Tuula Anneli Nyman, Victor Greiff, (2021). Progress and challenges in mass spectrometry-based analysis of antibody repertoires. Trends in Biotechnology s. 1-19. doi: 10.1016/j.tibtech.2021.08.006
- Mie Jareid, Igor Snapkov, Marit Holden, Lill-Tove Rasmussen Busund, Eiliv Lund, Therese Haugdahl Nøst, (2021). The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PLOS ONE s. 1-20. doi: 10.1371/journal.pone.0256442
- Åsa Kristina Øjlert, Daniel J.H. Nebdal, Igor Snapkov, Vibeke Olsen, Joel Kidman, Victor Greiff, Jonathan Chee, Åslaug Helland, (2021). Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor. Molecular Oncology s. 1-11. doi: 10.1002/1878-0261.13082
- Ramy A. Arnaout, Eline T. Luning Prak, Nicholas Schwab, Florian Rubelt, Victor Greiff, Milena Pavlović, Geir Kjetil Ferkingstad Sandve, Igor Snapkov, Rohit Arora, Rachael Bashford-Rogers, Felix Breden, Syed Ahmad Chan Bukhari, Brian Corrie, Lindsay G. Cowell, Sol Efroni, Christopher Gooley, Jason Vander Heiden, Yoshinobu Koguchi, Ton Langerak, Thean Soon Lim, Encarnita Mariotti-Ferrandiz, Susanna Marquez, Pieter Meysman, Enkelejda Miho, Keshav Motwani, Nima Nouri, Cinque Soto, Ulrik Stervbo, Johannes Trück, Henk-Jan van den Ham, Corey Watson, Cédric R. Weber, (2021). The Future of Blood Testing Is the Immunome. Frontiers in Immunology s. 1-6. doi: 10.3389/fimmu.2021.626793
- Rahmad Akbar, Philippe Paul Auguste Robert, Milena Pavlović, Jeliazko R. Jeliazkov, Igor Snapkov, Andrei Slabodkin, Cédric R. Weber, Lonneke Scheffer, Enkelejda Miho, Ingrid Hobæk Haff, Dag Trygve Truslew Haug, Fridtjof Lund-Johansen, Yana Safonova, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2021). A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding. Cell reports s. 1-21. doi: 10.1016/j.celrep.2021.108856
- Eiliv Lund, Marit Holden, Jean-Christophe Thalabard, Lill-Tove Rasmussen Busund, Igor Snapkov, Lars Holden, (2020). Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept. s. 141-162. doi: 10.18261/9788215041193-2020-09
- Cédric R. Weber, Rahmad Akbar, Alexander Yermanos, Milena Pavlovic, Igor Snapkov, Geir Kjetil Sandve, Sai T. Reddy, Victor Greiff, (2020). immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking. Bioinformatics s. 3594-3596. doi: 10.1093/bioinformatics/btaa158
- Alex Brown, Igor Snapkov, Rahmad Akbar, Milena Pavlovic, Enkelejda Miho, Geir Kjetil Sandve, Victor Greiff, (2019). Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires. Molecular Systems Design & Engineering s. 701-736. doi: 10.1039/c9me00071b
- Eiliv Lund, Aurelie Nakamura, Igor Snapkov, Jean-Christophe Thalabard, Karina Standahl Olsen, Lars Holden, Marit Holden, (2018). Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients.. Clinical Epidemiology doi: 10.2147/CLEP.S163208
- Conny Tümmler, Igor Snapkov, Malin Wickström, Ugo Moens, Linda Ljungblad, Maria Elfman, Jan-Olof Winberg, Per Kogner, John Inge Johnsen, Baldur Sveinbjørnsson, (2017). Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo. OncoTarget s. 95135-95151. doi: 10.18632/oncotarget.19619
- Cristina Ionica Øie, Igor Snapkov, Kjetil Elvevold, Baldur Sveinbjørnsson, Bård Smedsrød, (2016). FITC conjugation markedly enhances hepatic clearance of N-formyl peptides. PLOS ONE doi: 10.1371/journal.pone.0160602
- Igor Snapkov, Carl Otto Öqvist, Yngve Anton Figenschau, Per Kogner, John Inge Johnsen, Baldur Sveinbjørnsson, (2016). The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis. BMC Cancer doi: 10.1186/s12885-016-2545-1
- Nancy Gerits, Mona Johannessen, Conny Tümmler, Mari Walquist, Sergiy Kostenko, Igor Snapkov, Barbara van Loon, Elena Ferrari, Ulrich Hübscher, Ugo Moens, (2015). Agnoprotein of polyomavirus BK interacts With proliferating cell nuclear antigen and inhibits DNA replication. Virology Journal doi: 10.1186/s12985-014-0220-1
- Mie Linnea Jareid, Igor Snapkov, Marit Holden, Eiliv Lund, Therese Haugdahl Nøst, (2018). Transcriptional profiles of whole blood before a diagnosis of ovarian cancer.
- Conny Tümmler, Igor Snapkov, Ugo Moens, Baldur Sveinbjørnsson, (2014). Chemerin and chemerin receptors in neuroblastoma tumor microenvironment.
- Igor Snapkov, Per Kogner, John-Inge Johnsen, Baldur Sveinbjørnsson, (2014). Expression of formyl peptide receptor 1 (FPR1) in neuroblastoma: Implications in tumorigenesis.
- Yury Kiselev, Andrey Yurjevich Valkov, Lill-Tove Busund, Roy M. Bremnes, Igor Snapkov, Ingvild Mikkola, Thomas Karsten Kilvær, SW Sorbye, Eivind Smeland, Tom Dønnem, (2014). Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival.