Igor Snapkow
forsker, MD, PhD
Kontakt
Send e-post {model.translations.sendEmailTo} Igor.Snapkow@fhi.no
Avdeling
Fagområder
Lege; PhD i kreftimmunologi og inflammasjon; Postdok i immunreseptorbiologi og avanserte forskningsteknikker
Prosjekter og publikasjoner
- Anne-Cathrin Behr, Christiane Kruse Fæste, Amaya Azqueta, Ana M. Tavares, Anastasia Spyropoulou, Anita Solhaug, Ann-Karin Hardie Olsen, Ariane Vettorazzi, Birgit Mertens, Bojana Zegura, Camille Streel, Dieynaba Ndiaye, Eliana Spilioti, Estelle Dubreil, Franca Maria Buratti, Francesco Crudo, Gunnar Sundstøl Eriksen, Igor Snapkov, João Paulo Teixeira, Josef Rasinger, Julie Sanders, Kyriaki Machera, Lada Ivanova, Laurent Gaté, Ludovic Le Hegarat, Matjaz Novak, Nicola Margareta Smith, Sabrina Tait, Sónia Fraga, Sonja Hager, Doris Marko, Albert Braeuning, Henriqueta Louro, Maria João Silva, Hubert Dirven, Jessica Dietrich, (2025). Hazard characterization of the mycotoxins enniatins and beauvericin to identify data gaps and improve risk assessment for human health. Archives of Toxicology s. 1791-1841. doi: 10.1007/s00204-025-03988-3
- Habib Bashour, Eva Smorodina, Matteo Pariset, Jahn Zhong, Rahmad Akbar, Maria Chernigovskaia, Khang Le Quy, Igor Snapkov, Puneet Rawat, Konrad Krawczyk, Geir Kjetil Ferkingstad Sandve, Jose Gutierrez-Marcos, Daniel Nakhaee-Zadeh Gutierrez, Jan Terje Andersen, Victor Greiff, (2024). Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability. Communications Biology s. 1-25. doi: 10.1038/s42003-024-06561-3
- Igor Snapkov, Nicola Margareta Smith, Emma Arnesdotter, Karsten Beekmann, Etienne B. Blanc, Albert Braeuning, Emanuela Corsini, Marija Sollner Dolenc, Loes P.M. Duivenvoorde, Gunnar Sundstøl Eriksen, Nina Franko, Valentina Galbiati, Johanna M. Gostner, Nathalie Grova, Arno C. Gutleb, Rita Hargitai, Aafke Janssen, Solveig Krapf, Birgitte Lindeman, Katalin Lumniczky, Ambra Maddalon, Steen Kristen Mollerup, Lucia Parrakova, Arkadiusz Pierzchalski, Raymond H. H. Pieters, Maria J. Silva, Anita Solhaug, Yvonne Staal, Anne Straumfors, Tünde Szatmári, Jonathan David Turner, Rob J. Vandebriel, Ana Claudia Zenclussen, Robert Barouki, (2024). New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals — a PARC (Partnership for the Assessment of Risk from Chemicals) project. Frontiers in Toxicology doi: 10.3389/ftox.2024.1339104
- Quy Khang Le, Mariia Chernigovskaia, Maria Stensland, Sachin Singh, Jinwoo Leem, Santiago Revale, David A. Yadin, Francesca L. Nice, Chelsea Povall, Danielle H. Minns, Jacob D. Galson, Tuula Anneli Nyman, Igor Snapkov, Victor Greiff, (2024). Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling. npj Systems Biology and Applications doi: 10.1038/s41540-024-00402-z
- Henriqueta Louro, Ariane Vettorazzi, Adela López de Cerain, Anastasia Spyropoulou, Anita Solhaug, Anne Straumfors, Anne-Cathrin Behr, Birgit Mertens, Bojana Žegura, Christiane Kruse Fæste, Dieynaba Ndiaye, Eliana Spilioti, Elisabeth Varga, Estelle Dubreil, Eszter Borsos, Francesco Crudo, Gunnar Sundstøl Eriksen, Igor Snapkow, Jérôme Henri, Julie Sanders, Kyriaki Machera, Laurent Gaté, Ludovic Le Hegarat, Matjaž Novak, Nicola Margareta Smith, Solveig Krapf, Sonja Hager, Valérie Fessard, Yvonne Kohl, Maria João Silva, Hubert Dirven, Jessica Dietrich, Doris Marko, (2023). Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health. Archives of Toxicology s. 425-469. doi: 10.1007/s00204-023-03636-8
- Philippe Paul Auguste Robert, Rahmad Akbar, Robert Frank, Milena Pavlović, Michael Widrich, Igor Snapkov, Andrei Slabodkin, Maria Chernigovskaya, Lonneke Scheffer, Eva Smorodina, Puneet Rawat, Brij Bhushan Mehta, Mai Ha Vu, Ingvild Frøberg Mathisen, Aurél Prósz, Krzysztof Abram, Alex Olar, Enkelejda Miho, Dag Trygve Truslew Haug, Fridtjof Lund-Johansen, Sepp Hochreiter, Ingrid Hobæk Haff, Günter Klambauer, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2022). Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction. Nature Computational Science s. 845-865. doi: 10.1038/s43588-022-00372-4
- Rahmad Akbar, Philippe Paul Auguste Robert, Cédric R. Weber, Michael Widrich, Robert Frank, Milena Pavlovic, Lonneke Scheffer, Maria Chernigovskaia, Igor Snapkow, Andrei Slabodkin, Brij Bhushan Mehta, Enkelejda Miho, Fridtjof Lund-Johansen, Jan Terje Andersen, Sepp Hochreiter, Ingrid Hobæk Haff, Günter Klambauer, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2022). In silico proof of principle of machine learning-based antibody design at unconstrained scale. mAbs s. 1-18. doi: 10.1080/19420862.2022.2031482
- Andrei Slabodkin, Maria Chernigovskaia, Ivana Mikocziova, Rahmad Akbar, Lonneke Scheffer, Milena Pavlović, Habib Bashour, Igor Snapkov, Brij Bhushan Mehta, Cédric R. Weber, Jose Gutierrez-Marcos, Ludvig Magne Sollid, Ingrid Hobæk Haff, Geir Kjetil Ferkingstad Sandve, Philippe Paul Auguste Robert, Victor Greiff, (2021). Individualized VDJ recombination predisposes the available Ig sequence space. Genome Research s. 2209-2225. doi: 10.1101/gr.275373.121
- Milena Pavlović, Lonneke Scheffer, Keshav Motwani, Chakravarthi Kanduri, Radmila Kompova, Nikolay Aleksandrov Vazov, Knut Waagan, Fabian Leonardo Martinez Bernal, Alexandre Almeida Costa, Brian Corrie, Rahmad Akbar, Ghadi S. Al Hajj, Gabriel Balaban, Todd M. Brusko, Mariia Chernigovskaia, Scott Christley, Lindsay G. Cowell, Robert Frank, Ivar Grytten, Sveinung Gundersen, Ingrid Hobæk Haff, Eivind Hovig, Ping-Han Hsieh, Günter Klambauer, Marieke L. Kuijjer, Christin Lund-Andersen, Antonio Martini, Thomas Minotto, Johan Pensar, Knut Dagestad Rand, Enrico Riccardi, Philippe Paul Auguste Robert, Artur Rocha, Andrei Slabodkin, Igor Snapkov, Ludvig Magne Sollid, Dmytro Titov, Cédric R. Weber, Michael Widrich, Gur Yaari, Victor Greiff, Geir Kjetil Ferkingstad Sandve, (2021). The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires. Nature Machine Intelligence s. 936-944. doi: 10.1038/s42256-021-00413-z
- Igor Snapkov, Maria Chernigovskaia, Pavel Sinitcyn, Quy Khang Le, Tuula Anneli Nyman, Victor Greiff, (2021). Progress and challenges in mass spectrometry-based analysis of antibody repertoires. Trends in Biotechnology s. 1-19. doi: 10.1016/j.tibtech.2021.08.006
- Mie Jareid, Igor Snapkov, Marit Holden, Lill-Tove Rasmussen Busund, Eiliv Lund, Therese Haugdahl Nøst, (2021). The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PLOS ONE s. 1-20. doi: 10.1371/journal.pone.0256442
- Åsa Kristina Øjlert, Daniel J.H. Nebdal, Igor Snapkov, Vibeke Olsen, Joel Kidman, Victor Greiff, Jonathan Chee, Åslaug Helland, (2021). Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor. Molecular Oncology s. 1-11. doi: 10.1002/1878-0261.13082
- Ramy A. Arnaout, Eline T. Luning Prak, Nicholas Schwab, Florian Rubelt, Victor Greiff, Milena Pavlović, Geir Kjetil Ferkingstad Sandve, Igor Snapkov, Rohit Arora, Rachael Bashford-Rogers, Felix Breden, Syed Ahmad Chan Bukhari, Brian Corrie, Lindsay G. Cowell, Sol Efroni, Christopher Gooley, Jason Vander Heiden, Yoshinobu Koguchi, Ton Langerak, Thean Soon Lim, Encarnita Mariotti-Ferrandiz, Susanna Marquez, Pieter Meysman, Enkelejda Miho, Keshav Motwani, Nima Nouri, Cinque Soto, Ulrik Stervbo, Johannes Trück, Henk-Jan van den Ham, Corey Watson, Cédric R. Weber, (2021). The Future of Blood Testing Is the Immunome. Frontiers in Immunology s. 1-6. doi: 10.3389/fimmu.2021.626793
- Rahmad Akbar, Philippe Paul Auguste Robert, Milena Pavlović, Jeliazko R. Jeliazkov, Igor Snapkov, Andrei Slabodkin, Cédric R. Weber, Lonneke Scheffer, Enkelejda Miho, Ingrid Hobæk Haff, Dag Trygve Truslew Haug, Fridtjof Lund-Johansen, Yana Safonova, Geir Kjetil Ferkingstad Sandve, Victor Greiff, (2021). A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding. Cell reports s. 1-21. doi: 10.1016/j.celrep.2021.108856
- Eiliv Lund, Marit Holden, Jean-Christophe Thalabard, Lill-Tove Rasmussen Busund, Igor Snapkov, Lars Holden, (2020). Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept. s. 141-162. doi: 10.18261/9788215041193-2020-09
- Cédric R. Weber, Rahmad Akbar, Alexander Yermanos, Milena Pavlovic, Igor Snapkov, Geir Kjetil Sandve, Sai T. Reddy, Victor Greiff, (2020). immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking. Bioinformatics s. 3594-3596. doi: 10.1093/bioinformatics/btaa158
- Alex Brown, Igor Snapkov, Rahmad Akbar, Milena Pavlovic, Enkelejda Miho, Geir Kjetil Sandve, Victor Greiff, (2019). Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires. Molecular Systems Design & Engineering s. 701-736. doi: 10.1039/c9me00071b
- Eiliv Lund, Aurelie Nakamura, Igor Snapkov, Jean-Christophe Thalabard, Karina Standahl Olsen, Lars Holden, Marit Holden, (2018). Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients.. Clinical Epidemiology doi: 10.2147/CLEP.S163208
- Conny Tümmler, Igor Snapkov, Malin Wickström, Ugo Moens, Linda Ljungblad, Maria Elfman, Jan-Olof Winberg, Per Kogner, John Inge Johnsen, Baldur Sveinbjørnsson, (2017). Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo. OncoTarget s. 95135-95151. doi: 10.18632/oncotarget.19619
- Cristina Ionica Øie, Igor Snapkov, Kjetil Elvevold, Baldur Sveinbjørnsson, Bård Smedsrød, (2016). FITC conjugation markedly enhances hepatic clearance of N-formyl peptides. PLOS ONE doi: 10.1371/journal.pone.0160602
- Igor Snapkov, Carl Otto Öqvist, Yngve Anton Figenschau, Per Kogner, John Inge Johnsen, Baldur Sveinbjørnsson, (2016). The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis. BMC Cancer doi: 10.1186/s12885-016-2545-1
- Nancy Gerits, Mona Johannessen, Conny Tümmler, Mari Walquist, Sergiy Kostenko, Igor Snapkov, Barbara van Loon, Elena Ferrari, Ulrich Hübscher, Ugo Moens, (2015). Agnoprotein of polyomavirus BK interacts With proliferating cell nuclear antigen and inhibits DNA replication. Virology Journal doi: 10.1186/s12985-014-0220-1
- Henriqueta Louro, Ariane Vettorazzi, Adela López de Cerain, Anastasia Spyropoulou, Anita Solhaug, Anne Straumfors, Anne-Cathrin Behr, Birgit Mertens, Bojana Žegura, Christiane Kruse Fæste, Dieynaba Ndiaye, Eliana Spilioti, Elisabeth Varga, Estelle Dubreil, Eszter Borsos, Francesco Crudo, Gunnar Sundstøl Eriksen, Igor Snapkov, Jérôme Henri, Julie Sanders, Kyriaki Machera, Laurent Gaté, Ludovic Le Hegarat, Matjaž Novak, Nicola Margareta Smith, Solveig Krapf, Sonja Hager, Valérie Fessard, Yvonne Kohl, Maria João Silva, Hubert Dirven, Jessica Dietrich, Doris Marko, (2024). Correction to: Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health (Archives of Toxicology, (2024), 98, 2, (425-469), 10.1007/s00204-023-03636-8). Archives of Toxicology doi: 10.1007/s00204-024-03818-y
- Mie Linnea Jareid, Igor Snapkov, Marit Holden, Eiliv Lund, Therese Haugdahl Nøst, (2018). Transcriptional profiles of whole blood before a diagnosis of ovarian cancer.
- Conny Tümmler, Igor Snapkov, Ugo Moens, Baldur Sveinbjørnsson, (2014). Chemerin and chemerin receptors in neuroblastoma tumor microenvironment.
- Igor Snapkov, Per Kogner, John-Inge Johnsen, Baldur Sveinbjørnsson, (2014). Expression of formyl peptide receptor 1 (FPR1) in neuroblastoma: Implications in tumorigenesis.
- Yury Kiselev, Andrey Yurjevich Valkov, Lill-Tove Busund, Roy M. Bremnes, Igor Snapkov, Ingvild Mikkola, Thomas Karsten Kilvær, SW Sorbye, Eivind Smeland, Tom Dønnem, (2014). Transcription factor PAX6 is expressed in human soft tissue sarcomas and confers negative impact on patients' survival.