Benzodiazepine prescription and mortality among patients with benzodiazepine addiction in opioid maintenance treatment (OMT) - Protocol for a systematic review
Project
|Updated
The purpose of this systematic review is to investigate the effect on mortality after prescription of benzodazepines for benzodiazepine addiction to patients in OMT.
Summary
Benzodiazepines are commonly prescribed to patients in opioid maintenance treatment (OMT).
However, there is a lack of summarized research on the effects on mortality of prescribed benzodiazepines among people in OMT. The purpose of this systematic review is to investigate the effect on mortality after prescription of benzodazepines for benzodiazepine addiction to patients in OMT.
We will conduct a systematic literature search in electronic databases. Two reviewers will independently screen titles and abstracts to assess whether they meet our inclusion criteria. We will obtain references that we consider potentially relevant in full text, and we will then make a final assessment of which studies to include. We will extract and analyze data from the selected studies and evaluate each study’s risk of bias.
We will also rate our confidence in the results by assessing the certainty of the overall evidence by using the GRADE approach (Recommendations Assessment, Development and Evaluation).
Finally, we will present the included studies and overall results in a report.
Project leader
Christine Hillestad Hestevik, Norwegian Institute of Public Health
Project participants
Gyri Hval, Norwegian Institute of Public Health
Ashley Elizabeth Muller, Norwegian Institute of Public Health
Line Holtet Evensen, Norwegian Institute of Public Health
Start
01.05.2021
End
24.09.2021
Status
Concluded
Project owner/ Project manager
Norwegian Institute of Public Health