NORSE - Network for One Health Resistome Surveillance
NORSE is a consortium that will map the requirements for a resistome surveillance system, promote research and develop knowledge about the resistome and transmission of antimicrobial resistance, and promote dissemination of knowledge on AMR in a One Health perspective nationally and globally.
Om prosjektet
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Prosjektperiode: 01.01.2020 - 31.12.2026 (Aktivt)
- Koordinerende institutt: Norwegian Institute of Public Health
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Prosjektleder:
- Ulf Reidar Dahle, Infection Control and Preparedness, Norwegian Institute of Public Health
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Prosjektdeltakere:
- Geir Bukholm, Norwegian Institute of Public Health
- Mohammed Umaer Naseer, Norwegian Institute of Public Health
- Hilde Synnøve Vollan, Norwegian Institute of Public Health
- Ernst Kristian Rødland, Norwegian Institute of Public Health
- Anne Margrete Urdahl, Norwegian Veterinary Institute
- Fernanda Cristina Petersen, Institute of Oral Biology, University of Oslo
- Lin Cathrine T. Brandal, Norwegian Institute of Public Health
- Rafi Ahmad, Inland Norway University of Applied Sciences
- Gunnar Skov Simonsen, University Hospital of North Norway
- Andrea Sylvia Winkler, University of Oslo
- Yngvild Wasteson, Norges miljø- og biovitenskapelige universitet, Norwegian University of Life Sciences
- Ola Brønstad Brynildsrud, Method Development and Analytics, Norwegian Institute of Public Health
- Ekaterina Avershina, Department of Biotechnology, Inland Norway University of Applied Sciences
- Hege Salvesen Blix, Avdeling for legemiddelstatistikk, Norwegian Institute of Public Health
- Jon Bohlin, Method Development and Analytics, Norwegian Institute of Public Health
- Anders Bredberg, Div Lillehammer, Innlandet Hospital Trust
- Dominique Andree Yvette Caugant, Method Development and Analytics, Norwegian Institute of Public Health
- Birgitte Freiesleben de Blasio, Method Development and Analytics, Norwegian Institute of Public Health
- Jihong Liu Clarke, Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy Research
- Fasil Ejigu Eregno, Institutt for bygg, energi og materialteknologi, UiT The Arctic University of Norway
- Frode Forland, Infection Control Division Management, Norwegian Institute of Public Health
- Kirsten Midttun Gravningen, Infection Control and Preparedness, Norwegian Institute of Public Health
- Mohamed Gawad, Infection Control and Preparedness, Norwegian Institute of Public Health
- Thomas Hendricus Augustus Haverkamp, Epidemiologi, Norwegian Veterinary Institute
- Even Heir, Food safety and quality, Nofima, The Norwegian Institute of Food, Fisheries and Aquaculture Research
- Ingeborg Kathrina Haavardsson, Helsam Common Scientific Activities, University of Oslo
- Asbjørg Dyveke Johnsen, Administration, University of Oslo
- Knut Olav Strætkvern, Department of Biotechnology, Inland Norway University of Applied Sciences
- Aina Elisabeth Fossum Moen, Method Development and Analytics, Norwegian Institute of Public Health
- Bjørn-Arne Lindstedt, Kjemi, bioteknologi og matvitenskap, Norwegian University of Life Sciences
- Trude Marie Lyngstad, Infection Control and Preparedness, Norwegian Institute of Public Health
- Birgitte Moen, Food safety and quality, Nofima, The Norwegian Institute of Food, Fisheries and Aquaculture Research
- Arunima Sehgal Mukherjee, Digitalisation, University of Oslo
- Fredrik Müller, Department of Microbiology, Oslo University Hospital
- Kaare Magne Nielsen, Faculty of Health Sciences, Oslomet - Oslo Metropolitan University
- Snorre Hagen, Division of Environment and Natural Resources, Norwegian Institute of Bioeconomy Research
- Madelaine Norström, Epidemiologi, Norwegian Veterinary Institute
- Sundeep Sahay, Digitalisation, University of Oslo
- Henning Sørum, Institutt for parakliniske fag, Norwegian University of Life Sciences
- Arne Michael Taxt, Infection Control and Vaccines, Norwegian Institute of Public Health
- Tone Tønjum, Department of Microbiology, University of Oslo
- Francesco Di Ruscio, Method Development and Analytics, Norwegian Institute of Public Health
- Siamak Pour Yazdankhah, Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health
- Astrid Louise Wester, Bacteriology, Norwegian Institute of Public Health
- Sören Abel, Bacteriology, Norwegian Institute of Public Health
- Ågot Aakra, Climate and Environmental Health, Norwegian Institute of Public Health
- Kristiane Haug Berg, NCE Heidner Biocluster
- Frank Larsen, NCE Heidner Biocluster
Sammendrag
Antimicrobial resistance (AMR) is one of the biggest global health challenges of our time. In 2015, The World Health Organisation (WHO) launched a global action plan to address AMR and highlighted the need for a One Health approach to improve surveillance of antimicrobial resistance.Bacteria that have the ability to withstand exposure to antibiotics are termed resistant. Resistance is either intrinsic to the bacteria or acquired through favourable mutations or transfer of resistance genes between bacteria.Surveillance of AMR has focused on bacteria that cause disease. Research has shown that reservoirs of AMR genes circulate in the bacterial biosphere, in both commensal and pathogenic bacteria. This reservoir is termed the resistome. Studies have shown that transmission of resistance genes can occur between bacteria of the same species, as well as bacteria of different species and families. This means that antimicrobial resistance developed in a harmless bacteria can transfer to a potentially pathogenic bacteria.One Health is the understanding that human health is closely related to the health of animals and our environment. Bacteria are everywhere and AMR genes circulate not only in the human microbiome, but also in the environment and in animals.Improved surveillance of AMR is needed to better understand the transmission pathways of resistance in all One Health sectors, to enable better targeted interventions to limit the spread of AMR.The Network for One Health Resistome Surveillance (NORSE) is a consortium of public and private institutions, universities, hospitals and industry, with the following objective:1. To map the needs and requirements for a resistome surveillance system.2. To promote research and develop knowledge about the resistome, transmission of AMR, and data collection tools for resistome surveillance.3. To promote dissemination of knowledge on AMR in a One Health perspective nationally and globally.