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  • Operating room ventilation - revised edition

Health technology assessment

Operating room ventilation - a health technology assessment - revised edition

Published

We conducted a health technology assessment to evaluate the efficacy of laminar airflow (LAF) in reducing surgical site infections.

Forside rev Ventilasjon op-stuer.jpg

We conducted a health technology assessment to evaluate the efficacy of laminar airflow (LAF) in reducing surgical site infections.


Downloadable as PDF. In Norwegian. Key messages in English.

About this publication

  • Year: 2022
  • By: Norwegian Institute of Public Health
  • Authors Risstad H, Evensen LH, Movik E, Lerner M.
  • ISBN (digital): 978-82-8406-294-5

Key message

Surgical site infections are associated with increased morbidity and mortality. The role of the operating theatre ventilation system in preventing surgical site infections has been discussed for decades.

We conducted a health technology assessment to evaluate the efficacy of laminar airflow (LAF) in reducing surgical site infections. We included 22 observational studies. All studies were at moderate or serious risk of bias.  The effect estimates were imprecise, and there were somewhat lack of consistency of the results across the included studies. For the comparison of LAF with non-LAF, we found that:   

  • There were no difference in rates of serious surgical site infections (SSI) in all types of surgery and in joint prosthesis surgery (GRADE: low certainty)
  • There were no difference in rates of all SSIs in all types of surgery and in joint prosthesis surgery (GRADE: very low certainty)
  • We found no studies that provide sufficient information on the effect on mortality

We estimated the additional annual costs for one opeating theathre with LAF to be NOK 41 000 discounted over a 30-day period and 77 000 discounted over a 10-year period. The estimate is associated with uncertainty.

Revised version replaces version with ISBN number 978-82-8406-277-8, published 28.3.2022. More about the changes in the preface in the revised edition.