Summary

The background for this project is that the risk of asthma in children is higher when the mother has asthma than when the father has asthma.

Abstract:

So far no one has been able to explain the reason for this. If we find the cause of this inequality, it will be important for further research, and it may also be directly relevant to prevention. We will use Norwegian health registries and data from a large health study, the Norwegian Mother, Father and Child Study (MoBa) to test several hypotheses related to genes and the environment to understand the connection. We are concerned about exposures during pregnancy that may affect fetal development. The project has three main themes: A - to calculate maternal genetic effects with family data, B - to use molecular genetic methods, and C - to use data on environmental exposures during pregnancy.

See the full project description at Cristin for more information about results, researchers, contact information etc.

Project participants

Project leader

Per Magnus, Norwegian Institute of Public Health

Project participants

Maria Christine Magnus, Senter for fruktbarhet og helse, Norwegian Institute of Public Health
Siri Eldevik Håberg, Senter for fruktbarhet og helse, Norwegian Institute of Public Health
Astanand Jugessur, Avdeling for genetikk og bioinformatikk, Norwegian Institute of Public Health
Yunsung Lee, Avdeling for genetikk og bioinformatikk, Norwegian Institute of Public Health
Håkon Gjessing, Senter for fruktbarhet og helse, Norwegian Institute of Public Health
Line Cecilie Gjerde, Avdeling for psykiske lidelser, Norwegian Institute of Public Health
Espen Moen Eilertsen, Senter for fruktbarhet og helse, Norwegian Institute of Public Health
Miriam Gjerdevik, Senter for fruktbarhet og helse, Norwegian Institute of Public Health
Øystein Karlstad, Avdeling for kroniske sykdommer og aldring, Norwegian Institute of Public Health
Marianne Rørholt, Norwegian Institute of Public Health