Summary

The background for this project is that the risk of asthma in children is higher when the mother has asthma than when the father has asthma.

Abstract:

So far no one has been able to explain the reason for this. If we find the cause of this inequality, it will be important for further research, and it may also be directly relevant to prevention. We will use Norwegian health registries and data from a large health study, the Norwegian Mother, Father and Child Study (MoBa) to test several hypotheses related to genes and the environment to understand the connection. We are concerned about exposures during pregnancy that may affect fetal development. The project has three main themes: A - to calculate maternal genetic effects with family data, B - to use molecular genetic methods, and C - to use data on environmental exposures during pregnancy.

See the full project description at Cristin for more information about results, researchers, contact information etc.

Project participants

Project leader

Per Minor Magnus, Norwegian Institute of Public Health

Project participants

Maria Christine Magnus, Centre for Fertility and Health, Norwegian Institute of Public Health
Siri Eldevik Håberg, Centre for Fertility and Health, Norwegian Institute of Public Health
Astanand Jugessur, Genetics and Bioinformatics, Norwegian Institute of Public Health
Yunsung Lee, Genetics and Bioinformatics, Norwegian Institute of Public Health
Håkon Kristian Gjessing, Centre for Fertility and Health, Norwegian Institute of Public Health
Line Cecilie Gjerde, Mental Disorders, Norwegian Institute of Public Health
Espen Moen Eilertsen, Centre for Fertility and Health, Norwegian Institute of Public Health
Miriam Gjerdevik, Centre for Fertility and Health, Norwegian Institute of Public Health
Øystein Karlstad, Physical Health and Ageing, Norwegian Institute of Public Health
Marianne Hopen Rørholt, Norwegian Institute of Public Health