Chronic fatigue syndrome - ongoing clinical research studies
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Key message
The main purpose of the rapid review was to identify ongoing Norwegian clinical trials assessing effects of different types of interventions for people with chronic fatigue syndrome.
We searched for ongoing clinical trials in the WHO International Clinical Trials Registry Platform Search Portal (ICTRP) and the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) Clinical Trials Portal in March 2011.
We identified 45 registered protocols of clinical studies on the effect of treatment for chronic fatigue syndrome - six Norwegian, 12 Dutch, 14 American, nine English, three Australian, and one Belgian. The interventions were mainly pharmacological or behavioural- and attitude-related. Four protocols referred to Norwegian randomised controlled trials, two about pharmacological treatment (clonidine and rituximab) and two about behavioural- and attitude-related interventions.
It is useful to assemble ongoing clinical studies to see if current research activity covers any knowledge gaps identified for different types of interventions and outcomes in systematic reviews. There is ongoing clinical research on treatment interventions for people with chronic fatigue syndrome, and the number of studies initiated in Norway is high compared to other European countries. Of the 45 registered research protocols for ongoing clinical studies, are six Norwegian.