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  • Nye verktøy for tidlig predisposisjon til overvekt

Project

Novel Tools for Early Predisposition to Obesity - project description

Published

Here, we present a research program that can identify novel obesity risk genes for detection of early childhood obesity and diabetes.


Summary

Obesity is a primary indicator for development of type 2 diabetes and possibly cancer. These diseases are associated with significantly increased morbidity and mortality. Early presentation of obesity is linked to the degree of morbidity. Here, we present a research program that can identify novel obesity risk genes for detection of early childhood obesity and diabetes. In addition, this research program will identify common and rare genetic variants associated with obesity susceptibility and birth weight/childhood weight regulation. These findings may open up the possibility for new research fields on genetic epidemiology in obesity and diabetes investigations, mechanisms for how obesity and diabetes develop including expression studies of susceptibility genes in liver, muscle and fat tissues in subjects with obesity and/or diabetes, and targeted treatment by existing or novel drugs.

Project number

PDB 315

Start

01.09.2012

End

31.12.2032

Status

Active

Approvals

The Regional Committees for Medical and Health Research Ethics (REC). REK-nr: 18564

Project owner/ Project manager

Universitetet i Bergen

Project manager