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  • Using MoBa to understand the COVID-19 pandemic

Project

Using MoBa to understand the COVID-19 pandemic - project description

Published Updated

This project will follow the spread of COVID-19 disease in Norway over the next few years, and investigate why someone becomes infected and possibly seriously ill.


Summary

This project will follow the spread of Covid-19 disease in Norway over the next few years and try to understand why someone becomes infected and possibly seriously ill.

By utilizing an existing health survey called the Norwegian Mother, Father and Child Survey (MoBa), we will try to understand why someone becomes infected and possibly seriously ill from Covid-19.

The occurrence and consequences of Covid-19 depend on exposure to the virus, but also on the host and environmental factors. This necessitates both basic biological and epidemiological research. It seems that age combined with pre-existing disease is an important explanation for the severity. But even young people without previous illnesses can develop serious illness. For unknown reasons, men are more often hospitalized than women. The effects of socioeconomic background and previous health conditions can be studied using MoBa.

The MoBa data will also be linked to the following health registers:

  • KUHR - The database for control and payments of health reimbursement
  • NPR – The Norwegian Patient Register
  • MSIS - Norwegian Surveillance System for Communicable Diseases
  • SYSVAK - Norwegian Immunisation Registry

 

Here are examples of research questions in the project:

  • Estimate the association between host genetic factors and Covid-19 infection (by using MoBaGenetics on HUNT Cloud), including the development of long-term ailments (long COVID)
  • Test the hypothesis that obesity increases the risk of severe disease
  • Test the hypothesis that smoking increases the risk of severe disease
  • Test the hypothesis that other previous diseases, for example asthma and diabetes, increase the risk of severe disease
  • Compare the prevalence of mental health problems, for example anxiety, using new questionnaires, with earlier measures of the same problems, and follow these problems over time
See the full project description at Cristin for more information about results, researchers, contact information etc.

Project participants

Project leader

Per Minor Magnus, Norwegian Institute of Public Health

Project participants

Lill-Iren Schou Trogstad, Development and Analytics, Norwegian Institute of Public Health
Maria Christine Magnus, Centre for Fertility and Health, Norwegian Institute of Public Health
Yunsung Lee, Genetics and Bioinformatics, Norwegian Institute of Public Health
Ellen Øen Carlsen, Centre for Fertility and Health, Norwegian Institute of Public Health
Elin Hilde Roti Alsaker, Health Studies, Norwegian Institute of Public Health
Siri Eldevik Håberg, Centre for Fertility and Health, Norwegian Institute of Public Health
Øyvind Helgeland, Genetics and Bioinformatics, Norwegian Institute of Public Health
Astanand Jugessur, Genetics and Bioinformatics, Norwegian Institute of Public Health

Project number

PDB 2824

Start

01.04.2020

End

31.03.2024

Status

Active

Approvals

Regional committees for medical and health research ethics

Project owner/ Project manager

Norwegian Institute of Public Health

Project manager

Per Minor Magnus