Plasma concentrations of poly- and perfluoroalkyl substances (PFASs) in pregnant women and the association with child's prenatal and postnatal growth.
Project
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We will investigate how exposure to PFAS during pregnancy can affect fetal growth within a large meta-analysis of European birth cohorts.
Summary
High exposure to pollutants in vulnerable life stages, especially in fetal life can adversely affect the fetus and “program” disease later in life. Poly- and perfluoroalkyl substances (PFASs) make up a large group of persistent anthropogenic chemicals used in industrial processes and commercial products over the past 60 years. PFAS are found in blood samples of Norwegian pregnant women. By using existing data from the Norwegian mother and child cohort study we will investigate how exposure to PFAS during pregnancy can affect fetal growth within a large meta-analysis of European birth cohorts. Further, we will provide knowledge on how exposure to PFAS in pregnancy can affect growth, weight development and metabolic disturbances in Norwegian children. Finally we will explore if the PFAS levels of the pregnant women are clustered in specific geographical areas around the country.
Project leader
Line Småstuen Haug, Norwegian Institute of Public Health
Project participants
Line Småstuen Haug, Infection Control, Norwegian Institute of Public Health
Helle Margrete Meltzer, Infection Control, Norwegian Institute of Public Health
Gro Dehli Andersen, Norwegian Institute of Public Health
Heidi Aase, Norwegian Institute of Public Health
Thorhallur Ingi Halldórsson, University of Iceland
Cathrine Thomsen, Norwegian Institute of Public Health
Eleni Papadopoulou, Norwegian Institute of Public Health
About the project
Start
01.03.2018
End
31.12.2025
Status
Active
Approvals
Regional committees for medical and health research ethics
Project owner/ Project manager
Norwegian Institute of Public Health