Mild- to moderate iodine deficiency in pregnancy and early age and risk of impaired neuropsychological development
Project
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The aim of this project was to explore the associations between maternal iodine intake in pregnancy from food and supplements and markers of child brain development in The Norwegian Mother and Child Cohort Study
Summary
Iodine is an integral part of the thyroid hormones that are essential in foetal brain development and iodine deficiency is the world’s most prevalent, yet easily preventable, cause of brain damage. Severe iodine deficiency in pregnancy has detrimental effects on foetal neurodevelopment, whereas less is known about the potential consequences of mild-to-moderate iodine deficiency. The aim of this project was to explore the associations between maternal iodine intake in pregnancy from food and supplements and markers of child brain development in The Norwegian Mother and Child Cohort Study (MoBa). Additionally, in a subsample of around 3000 women, we aimed to examine associations between maternal iodine status and maternal thyroid function. Four papers have been published in this project so far and the results indicate that low maternal iodine intake is associated with impaired neurodevelopmental outcomes in children at 3 and 8 years.
Project leader
Anne Lise Brantsæter, Norwegian Institute of Public Health
Project participants
Marianne Hope Abel, OsloMet - Oslo Metropolitan University, Oslomet - Oslo Metropolitan University
Liv Elin Torheim, OsloMet - Oslo Metropolitan University, Oslomet - Oslo Metropolitan University
Ida Henriette Caspersen, Infection Control, Norwegian Institute of Public Health
Helle Margrete Meltzer, Infection Control, Norwegian Institute of Public Health
Alice Margareta Haugen, Infection Control, Norwegian Institute of Public Health
Jan Alexander, Infection Control, Norwegian Institute of Public Health
Heidi Aase, Child Health and Development, Norwegian Institute of Public Health
Ragnhild Eek Brandlistuen, Child Health and Development, Norwegian Institute of Public Health
Gro Dehli Villanger, Child Health and Development, Norwegian Institute of Public Health
Guido Philipp Emmanuel Biele, Child Health and Development, Norwegian Institute of Public Health
Tim Korevaar, University Medical Center Rotterdam
Iris Erlund, National Institute for Health and Welfare
Petra Arohonka, National Institute for Health and Welfare
About the project
Start
01.09.2014
End
21.06.2022
Status
Concluded
Approvals
Regional committees for medical and health research ethics
Project owner/ Project manager
Norwegian Institute of Public Health