Plasma concentrations of poly- and perfluoroalkyl substances (PFASs) in pregnant women and the association with child's prenatal and postnatal growth.
We will investigate how exposure to PFAS during pregnancy can affect fetal growth within a large meta-analysis of European birth cohorts.
About the project
-
Project period: 01.03.2018 - 31.12.2027 (Active)
- Coordinating Institution: Norwegian Institute of Public Health
-
Project Manager:
- Line Småstuen Haug, Norwegian Institute of Public Health
-
Project Participants:
- Line Småstuen Haug, Infection Control, Norwegian Institute of Public Health
- Helle Margrete Meltzer, Infection Control, Norwegian Institute of Public Health
- Gro Dehli Andersen, Norwegian Institute of Public Health
- Heidi Aase, Norwegian Institute of Public Health
- Thorhallur Ingi Halldórsson, University of Iceland
- Cathrine Thomsen, Norwegian Institute of Public Health
- Eleni Papadopoulou, Norwegian Institute of Public Health
Summary
High exposure to pollutants in vulnerable life stages, especially in fetal life can adversely affect the fetus and “program” disease later in life. Poly- and perfluoroalkyl substances (PFASs) make up a large group of persistent anthropogenic chemicals used in industrial processes and commercial products over the past 60 years. PFAS are found in blood samples of Norwegian pregnant women. By using existing data from the Norwegian mother and child cohort study we will investigate how exposure to PFAS during pregnancy can affect fetal growth within a large meta-analysis of European birth cohorts. Further, we will provide knowledge on how exposure to PFAS in pregnancy can affect growth, weight development and metabolic disturbances in Norwegian children. Finally we will explore if the PFAS levels of the pregnant women are clustered in specific geographical areas around the country.