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Vaccine against HPV (human papilloma virus)

The HPV vaccine has been offered to girls in 7th grade since the 2009/2010 school year. From autumn 2018, boys will also be offered the vaccine. Boys and girls will have an equal opportunity to protect themselves against cancers caused by HPV (human papilloma virus).

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When children are offered a vaccine, their opinion must be considered.

How is the vaccine given?

The vaccine will be injected in your upper arm. Two doses are given, with a gap of at least six months in between. Before vaccination, your school health nurse will ask if you are feeling well and if you have reacted to any other vaccines. Tell the nurse if you have any allergies, use medicines or have any other health problems.

You can take the vaccine if you have a cold or are feeling slightly unwell. It is common to postpone vaccination if you are ill or have a fever over 38 degrees.

You can exercise after vaccination if you feel up to it.

Protects against cancer in both sexes

HPV is a very common virus and there are many different strains. The virus is easily transmitted by sexual contact and most people will have one or more HPV infections during their life. Young people are those most commonly infected.

Many people who are infected display no symptoms. Most HPV infections usually clear up within a few months. Sometimes the infection can persist and lead to pre-cancerous lesions and cancer.

The most common form of cancer caused by HPV is cervical cancer in women. HPV can also lead to cancer of the rectum, mouth and throat in both sexes. HPV can also lead to cancer of the vagina and external genitalia in women, and the penis in men. The HPV vaccine can help to protect against all these cancers.

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More about cervical cancer and other cancers caused by HPV

Every year in Norway, approximately 350 women will develop cervical cancer and 60-100 women will die.

More than 3,000 women undergo surgery for severe pre-cancerous lesions every year. Pregnant women who have had this surgery may be at increased risk of miscarriage or premature birth.

Every year, between 200 and 300 women and men develop HPV-related cancer in other organs than the cervix. These include the mouth, throat and rectum in both sexes, as well as the vagina and external genitalia (women) and the penis (men). These cancer cases are equally distributed between women and men. Mouth and throat cancer are most common in men and the number of cases is increasing.

How does the HPV vaccine work?

The HPV vaccine is a preventive medicine. It gives the best protection when given before exposure to infection. Children are offered the HPV vaccine in the 7th grade as part of the Childhood Immunisation Programme, before they become sexually active.

The vaccine consists of proteins that resemble those on the surface of the virus. The vaccine does not contain live viruses and cannot cause HPV infection.

The vaccine gives an equally good immune response in boys and girls. Studies of pre-cancerous lesions show that the vaccine provides more than 90 per cent protection among women who were vaccinated before exposure to HPV infection.

Studies also show that the HPV vaccine is effective up to 10-12 years after vaccination and there is no evidence yet that protection is impaired over time. The follow-up of vaccinated individuals will show whether a booster dose is necessary later in life to maintain protection.

Side effects

Like all medicines, vaccines may cause side effects. The most common side effects from the HPV vaccine are temporary:

  • Tenderness, redness and swelling of the arm at the site of vaccination. This is very common (experienced by more than 1 in 10 individuals)
  • Headache, fatigue or muscle ache. This is very common (experienced by more than 1 in 10 individuals).
  • Fever, joint pain, itching, rash, nausea, vomiting / diarrhoea or abdominal pain are common (experienced by 1-10 in 100 individuals)

Dizziness, feeling faint or fainting are usually due to discomfort or anxiety because of the injection, and not the vaccine.

Severe allergic reactions are rare and arise shortly after vaccination. The school health nurse will ask you to wait for approximately 20 minutes after vaccination, and will be prepared to handle such situations.

There is no evidence to suggest that HPV vaccine is the cause of chronic or severe disease or increases the risk. Symptoms that arise after vaccination are not necessarily due to the vaccine but may be signs of a disease that needs medical attention. Consult your doctor if you are concerned. Healthcare professionals are obliged to report any suspected side effects to the medicine authorities.

Useful to know

  • The World Health Organization (WHO) recommends that the HPV vaccine should be included in national childhood immunisation programmes. 82 countries have included the vaccine in their programme and 12 of them offer it to boys.
  • The vaccine used in the Norwegian programme is Cervarix. More information about the vaccine is available from the Norwegian Medicines Agency’s website. 
  • Cervarix is ​​used in the programmes of 29 countries and more than 64 million doses of this vaccine have been given.
  • None of the vaccines offered in the programme contain mercury as a preservative, including the HPV vaccine.
  • Condoms do not provide complete protection against HPV infection because the virus is present on the skin around the genitals. Condoms protect against other sexually transmitted diseases.
  • Some HPV types may lead to genital warts. Cervarix does not protect against this.
  • The HPV vaccine does not protect against all the HPV types that cause cancer. Women should still participate in the Cervical Screening Programme every third year from the age of 25 years.
  • There are no screening programmes for the other HPV-related cancers.

HPV vaccination is recorded in the National Immunisation Registry SYSVAK. To parents / guardians: you can see the immunisation status for you and your children under the age of 16 years with the Vaccines service at www.helsenorge.no. You can also print a vaccination certificate in Norwegian and English.