Fagområder
Medisinsk fysikk, strålingsbiologi, bildediagnostikk, preklinisk kreftforskning
Faglig bakgrunn
Jon-Vidar Gaustad er forsker ved klynge for vurdering av tiltak, helse. Han har tidligere vært forsker ved Institutt for Kreftforskning, Oslo Unviersitetssykehus.
Prosjekter og publikasjoner
- Effekt av psykososiale tiltak for personer med demens - Prosjektplan for en oversikt over oversikter
- HPV-test i screeningprogrammet mot livmorhalskreft for aldersgruppen 25-33 år - Prosjektplan for en systematisk oversikt
- Psykologisk debriefing for helse-personell som har vært involvert i uønskede pasienthendelser - Prosjektplan for en systematisk oversikt
- Jon-Vidar Gaustad, Einar K Rofstad, (2021). Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI. Frontiers in Oncology doi: 10.3389/fonc.2021.668916
- Jon-Vidar Gaustad, Einar K Rofstad, (2021). Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods. Frontiers in Oncology doi: 10.3389/fonc.2021.722773
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Hansem, Einar K Rofstad, (2021). Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope. European Journal of Nuclear Medicine and Molecular Imaging s. 3089-3100. doi: 10.1007/s00259-021-05243-0
- Jahn Otto Waldeland, Jon-Vidar Gaustad, Einar K Rofstad, Steinar Evje, (2021). In silico investigations of intratumoral heterogeneous interstitial fluid pressure. Journal of Theoretical Biology s. 1-21. doi: 10.1016/j.jtbi.2021.110787
- Jon-Vidar Gaustad, Anette Hauge, Catherine E Sem Wegner, Trude Golimo Simonsen, Kjersti Vassmo Lund, Lise Mari Klepp Andersen, Einar K Rofstad, (2020). DCE-MRI of tumor hypoxia and hypoxia-associated aggressiveness. Cancers s. 1-15. doi: 10.3390/cancers12071979
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Einar K Rofstad, (2020). Bevacizumab treatment of meningeal melanoma metastases. Journal of Translational Medicine s. 1-12. doi: 10.1186/s12967-020-02212-3
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Catherine E Sem Wegner, Einar K Rofstad, (2019). Vascularization, oxygenation, and the effect of sunitinib treatment in pancreatic ductal adenocarcinoma xenografts. Frontiers in Oncology doi: 10.3389/fonc.2019.00845
- Lise Mari Klepp Andersen, Ruixia Huang, Catherine E Sem Wegner, Trude Golimo Simonsen, Jon-Vidar Gaustad, Anette Hauge, Einar K Rofstad, (2019). Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts. Translational Oncology s. 1079-1085. doi: 10.1016/j.tranon.2019.05.012
- Anette Hauge, Jon-Vidar Gaustad, Ruixia Huang, Trude Golimo Simonsen, Catherine E Sem Wegner, Lise Mari Klepp Andersen, Einar K Rofstad, (2019). DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma. International Journal of Radiation Oncology, Biology, Physics s. 666-676. doi: 10.1016/j.ijrobp.2019.03.002
- Catherine E Sem Wegner, Anette Hauge, Lise Mari Klepp Andersen, Ruixia Huang, Trude Golimo Simonsen, Jon-Vidar Gaustad, Einar K Rofstad, (2018). Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation. OncoTarget s. 21036-21051. doi: 10.18632/oncotarget.24783
- Anette Hauge, Catherine E Sem Wegner, Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2018). Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy. Translational Oncology s. 1128-1136. doi: 10.1016/j.tranon.2018.07.005
- Catherine E Sem Wegner, Anette Hauge, Trude Golimo Simonsen, Jon-Vidar Gaustad, Lise Mari Klepp Andersen, Einar K Rofstad, (2018). DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts. Neoplasia s. 734-744. doi: 10.1016/j.neo.2018.05.006
- Anette Hauge, Catherine E Sem Wegner, Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2017). Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer. OncoTarget s. 105682-105691. doi: 10.18632/oncotarget.22388
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2017). Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts. Journal of Translational Medicine doi: 10.1186/s12967-017-1347-9
- Anette Hauge, Catherine E Sem Wegner, Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2017). DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: Associations with parameters of the tumor microenvironment. Journal of Translational Medicine doi: 10.1186/s12967-017-1331-4
- Catherine E Sem Wegner, Anette Hauge, Jon-Vidar Gaustad, Lise Mari Klepp Andersen, Trude Golimo Simonsen, Liyana Dayakanthi Galappathi, Einar K Rofstad, (2017). Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts. Acta Oncologica s. 1754-1762. doi: 10.1080/0284186X.2017.1343494
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2017). Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts. BMC Cancer s. 1-7. doi: 10.1186/s12885-017-3404-4
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2017). The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles. Translational Oncology s. 158-167. doi: 10.1016/j.tranon.2016.12.007
- Lise Mari Klepp Andersen, Catherine E Sem Wegner, Trude Golimo Simonsen, Ruixia Huang, Jon-Vidar Gaustad, Anette Hauge, Liyana Dayakanthi Galappathi, Einar K Rofstad, (2017). Lymph node metastasis and the physicochemical microenvironment of pancreatic ductal adenocarcinoma xenografts. OncoTarget s. 48060-48074. doi: 10.18632/oncotarget.18231
- Catherine E Sem Wegner, Jon-Vidar Gaustad, Lise Mari Klepp Andersen, Trude Golimo Simonsen, Einar K Rofstad, (2016). Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content. Journal of Translational Medicine doi: 10.1186/s12967-016-0920-y
- Einar K Rofstad, Trude Golimo Simonsen, Ruixia Huang, Lise Mari Klepp Andersen, Liyana Dayakanthi Galappathi, Christine Ellingsen, Catherine E Sem Wegner, Anette Hauge, Jon-Vidar Gaustad, (2016). Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix. Cancer Letters s. 147-155. doi: 10.1016/j.canlet.2016.01.047
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp Andersen, Einar K Rofstad, (2016). Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression. OncoTarget s. 76806-76815. doi: 10.18632/oncotarget.12695
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Einar K Rofstad, (2016). Intracranial tumor cell migration and the development of multiple brain metastases in malignant melanoma. Translational Oncology s. 211-218. doi: 10.1016/j.tranon.2016.04.003
- Einar K Rofstad, Ruixia Huang, Liyana Dayakanthi Galappathi, Lise Mari Klepp Andersen, Catherine E Sem Wegner, Anette Hauge, Jon-Vidar Gaustad, Trude Golimo Simonsen, (2016). Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: Implications for lymph node metastasis. OncoTarget s. 56986-56997. doi: 10.18632/oncotarget.10931
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Ragnhild Smistad, Catherine E Sem Wegner, Lise Mari Klepp Andersen, Einar K Rofstad, (2015). Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging. BMC Cancer s. 1-10. doi: 10.1186/s12885-015-1918-1
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Einar K Rofstad, (2015). Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-015-0264-0
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Lise Mari Klepp-Andersen, Einar K Rofstad, (2015). Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts. Microvascular Research s. 159-165. doi: 10.1016/j.mvr.2014.02.005
- Jon-Vidar Gaustad, Viktoria Pozdniakova, Tord Hompland, Trude Golimo Simonsen, Einar K Rofstad, (2013). Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts. Journal of Experimental and Clinical Cancer Research doi: 10.1186/1756-9966-32-93
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Ana Maria Acosta Roa, Einar K Rofstad, (2013). Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply. Microvascular Research s. 10-15. doi: 10.1016/j.mvr.2012.11.002
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Marit Nedkvitne Leinaas, Einar K Rofstad, (2013). Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts. Microvascular Research s. 16-23. doi: 10.1016/j.mvr.2012.11.001
- Tormod Andre Mjelde Egeland, Kristine Gulliksrud, Jon-Vidar Gaustad, Berit Synnøve Mathiesen, Einar K Rofstad, (2012). Dynamic contrast-enhanced-MRI of tumor hypoxia. Magnetic Resonance in Medicine s. 519-530. doi: 10.1002/mrm.23014
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Marit Nedkvitne Leinaas, Einar K Rofstad, (2012). High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts. PLOS ONE doi: 10.1371/journal.pone.0040006
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Mari Leinaas, Einar K Rofstad, (2012). Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts. BMC Cancer doi: 10.1186/1471-2407-12-388
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Mari Leinaas, Einar K Rofstad, (2012). Vascular abnormalities associated with acute hypoxia in human melanoma xenografts. Radiotherapy and Oncology s. 72-78. doi: 10.1016/j.radonc.2012.08.018
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Mari Leinaas, Einar K Rofstad, (2012). A novel application of dorsal window chambers: Repetitive imaging of tumor-associated lymphatics. Microvascular Research s. 360-365. doi: 10.1016/j.mvr.2012.02.003
- Tormod Andre Mjelde Egeland, Jon-Vidar Gaustad, Liyana Dayakanthi Galappathi, Einar K Rofstad, (2011). Magnetic resonance imaging of tumor necrosis. Acta Oncologica s. 427-434. doi: 10.3109/0284186X.2010.526633
- Einar K Rofstad, Jon-Vidar Gaustad, Torstein Egeland, Berit Mathiesen, Kanthi Galappathi, (2010). Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination. International Journal of Cancer s. 1535-1546. doi: 10.1002/ijc.25176
- Trude Golimo Simonsen, Jon-Vidar Gaustad, Einar K Rofstad, (2010). DEVELOPMENT OF HYPOXIA IN A PRECLINICAL MODEL OF TUMOR MICROMETASTASES. International Journal of Radiation Oncology, Biology, Physics s. 879-888. doi: 10.1016/j.ijrobp.2009.09.045
- Christine Ellingsen, Ingrid Natvig, Jon-Vidar Gaustad, Kristine Gulliksrud, Tormod Andre Mjelde Egeland, Einar K Rofstad, (2009). Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors. Journal of Cancer Research and Clinical Oncology s. 1177-1184. doi: 10.1007/s00432-009-0558-8
- Tormod Andre Mjelde Egeland, Trude Golimo Simonsen, Jon-Vidar Gaustad, Kristine Gulliksrud, Christine Ellingsen, Einar K Rofstad, (2009). Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Tumors: Preclinical Validation of Parametric Images. Radiation Research s. 339-347. doi: 10.1667/RR1787.1
- Einar K Rofstad, Jon-Vidar Gaustad, Kjetil Gundro Brurberg, Berit Synnøve Mathiesen, Liyana Dayakanthi Galappathi, Trude Golimo Simonsen, (2009). Radiocurability Is Associated with Interstitial Fluid Pressure in Human Tumor Xenografts. Neoplasia s. 1243-1251. doi: 10.1593/neo.91152
- Ole-Jacob Anderssen Norum, Jon-Vidar Gaustad, Even Angell-Petersen, Einar K Rofstad, Peng Qian, Karl-Erik Giercksky, Alf Kristian Berg, (2009). Photochemical Internalization of Bleomycin is Superior to Photodynamic Therapy Due to the Therapeutic Effect in the Tumor Periphery. Photochemistry and Photobiology s. 740-749. doi: 10.1111/j.1751-1097.2008.00477.x
- Christine Ellingsen, Tormod Andre Mjelde Egeland, Kristine Gulliksrud, Jon-Vidar Gaustad, Berit Synnøve Mathiesen, Einar K Rofstad, (2009). Assessment of Hypoxia in Human Cervical Carcinoma Xenografts by Dynamic Contrast-Enhanced Magnetic Resonance Imaging. International Journal of Radiation Oncology, Biology, Physics s. 838-845. doi: 10.1016/j.ijrobp.2008.10.062
- Jon-Vidar Gaustad, Trude Golimo Simonsen, Kjetil Gundro Brurberg, Else Marie Huuse, Einar K Rofstad, (2009). Blood Supply in Melanoma Xenografts Is Governed by the Morphology of the Supplying Arteries. Neoplasia s. 277-285. doi: 10.1593/neo.81400
- Jon-vidar Gaustad, Ilana Benjaminsen, Bjørn Anton Graff, Kjetil G. Brurberg, Else-Beate M. Ruud, Einar Rofstad, (2005). Intratumor Heterogeneity in Blood Perfusion in Orthotopic Human Melanoma Xenografts Assessed by Dynamic Contrast-Enhanced Magnetic Resonance Imaging. Journal of Magnetic Resonance Imaging s. 792-800.
- Gunn Elisabeth Vist, Jon-Vidar Gaustad, Gyri Hval, Vigdis Underland, (2022). Effekt av psykososiale tiltak for personer med demens: oversikt over systematiske oversikter
- Jon-Vidar Gaustad, Randi Ingebjørg Krontveit, Martin Smådal Larsen, (2022). HPV-test i screeningprogrammet mot livmorhalskreft for aldersgruppen 25-33 år: systematisk oversikt
- Patricia Sofia Jacobsen Jardim, Jon-Vidar Gaustad, Lars Jørun Langøien, Gunn Eva Næss, (2022). Omfang av seksuell trakassering i Norge: en hurtigoversikt
- Jose Francisco Meneses Echavez, Tiril Cecilie Borge, Henriette Tyse Nygård, Jon-Vidar Gaustad, Gyri Hval, (2022). Psykologisk debriefing for helsepersonell involvert i uønskede pasienthendelser: en systematisk oversikt
- Jon-Vidar Gaustad, Linn Kleven, Hege Kornør, Ingrid Harboe, Annette Vogt Flatby, Eivind Aakhus, Martin Kragnes Bystad, Ingvild Røste, (2022). Transkraniell likestrømsbehandling for depresjon og afasi: fullstendig metodevurdering
- Kristine Gulliksrud, Tormod Andre Mjelde Egeland, Jon-Vidar Gaustad, Einar K Rofstad, (2010). Interstitial fluid pressure of tumors as a function of parameters derived by dynamic contrast-enhanced magnetic resonance imaging: Response to letter by Farace and Boschi. Radiotherapy and Oncology s. 385-386. doi: 10.1016/j.radonc.2009.12.025