Didrik Frimann Vestrheim
Avdelingsdirektør, Cand.med. PhD
Prosjekter og publikasjoner
Prosjekter
- Effekt av pneumokokkvaksine hos eldre i Norge
- Epidemiologi og molekylær karakterisering av invasive gruppe A streptokokkinfeksjoner i Norge, 2015-2018
- Evolusjon av Bordetella pertussis i Norge, 1996-2019: Allelvarianter av vaksine relaterte antigener
- I-MOVE+ (personer 65 år eller eldre)
- Kikhoste epidemiologien med fokus på effekten av boostervaksinene i den Norske barnevaksinasjonsprogrammet på den alders-spesifikke kikhoste insidensen
- Klonale endringer og antibiotikaresistens blant invasive pneumokokker etter vaksineintroduksjon
- MINI-Nor-studien - Immunitet mot vaksineforebyggbare sykdommer hos gravide kvinner og deres barn
- Pneumokokk serotypedistribusjon blant risikogrupper
- Pneumokokker blant barn i Norge
- Pneumokokker blant barn i Norge
- Pneumokokker ved øvre luftveisinfeksjoner - Serotypefordeling, klonalitet og resistensforhold ved introduksjon av konjugert pneumokokkvaksine i barnevaksinasjonsprogrammet. Undersøkelse av bakterieisolater samlet inn gjennom NORM
- Seroprevalensstudie for kikhoste og andre vaksineforebyggbare sykdommer i Norge
- SpIDnet II (yngre enn 65 år)
- Styrket overvåking av systemisk pneumokokksykdom hos barn og voksne i Norge og Europa
- Vaksinasjonsdekning og spredningspotensiale for smittsomme sykdommer i Norge
Vitenskapelige artikler og bokkapitler
- Hans Kristian Floeystad, Jacob Dag Berild, Bjoern Jardar Brandsaeter, Didrik Frimann Vestrheim, Dag Berild, Are Martin Holm, (2020). Gastrointestinal symptoms in invasive pneumococcal disease: A cohort study. BMC Infectious Diseases doi: 10.1186/s12879-020-05211-3
- Lotta Siira, Didrik Frimann Vestrheim, Brita Askeland Winje, Dominique Caugant, Anneke Steens, (2020). Antimicrobial susceptibility and clonality of Streptococcus pneumoniae isolates recovered from invasive disease cases during a period with changes in pneumococcal childhood vaccination, Norway, 2004–2016. Vaccine doi: 10.1016/j.vaccine.2020.06.040
- Jacob Dag Berild, Brita Askeland Winje, Didrik Frimann Vestrheim, Hans-Christian Slotved, Palle Valentiner-Branth, Adam Roth, Jann Storsäter, (2020). A systematic review of studies published between 2016 and 2019 on the effectiveness and efficacy of pneumococcal vaccination on pneumonia and invasive pneumococcal disease in an elderly population. Pathogens s. 1-15. doi: 10.3390/pathogens9040259
- Astrid Louise Løvlie, Didrik Frimann Vestrheim, Ingeborg Sundsvalen Aaberge, Anneke Steens, (2020). Changes in pneumococcal carriage prevalence and factors associated with carriage in Norwegian children, four years after introduction of PCV13. BMC Infectious Diseases doi: 10.1186/s12879-019-4754-0
- Kjersti Sturød, Achal Dhariwal, Ulf R Dahle, Didrik Frimann Vestrheim, Fernanda Cristina Petersen, (2019). Impact of narrow-spectrum penicillin V on the oral and faecal resistome in a young child treated for otitis media. Journal of Global Antimicrobial Resistance s. 290-297. doi: 10.1016/j.jgar.2019.08.004
- Alex-Mikael Barkoff, Jussi Mertsola, Denis Pierard, Tine Dalby, Silje Vermedal Høgh, Sophie Guillot, Paola Stefanelli, Marjolein van Gent, Guy Berbers, Didrik Frimann Vestrheim, Margrethe Greve-Isdahl, Lena Wehlin, Margaretha Ljungman, Norman K. Fry, Kevin Markey, Qiushui He, (2019). Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015. Eurosurveillance doi: 10.2807/1560-7917.ES.2019.24.7.1700832
- Anneke Steens, Brita Askeland Winje, Richard Aubrey White, Ingvild Odsbu, Arne Broch Brantsæter, Didrik Frimann Vestrheim, (2019). Indirect effects of pneumococcal childhood vaccination in individuals treated with immunosuppressants in ambulatory care: a case-cohort study. Clinical Infectious Diseases s. 1367-1373. doi: 10.1093/cid/ciy714
- Germaine Hanquet, Pavla Krizova, Palle Valentiner-Branth, Shamez N. Ladhani, J. Pekka Nuorti, Agnes Lepoutre, Jolita Mereckiene, Mirjam Knol, Brita Askeland Winje, Pilar Ciruela, Maria Ordobas, Marcela Guevara, Eisin McDonald, Eva Morfeldt, Jana Kozakova, Hans-Christian Slotved, Norman K. Fry, Hanna Rinta-Kokko, Emmanuelle Varon, Mary Corcoran, Arie van der Ende, Didrik Frimann Vestrheim, Carmen Muñoz-Almagro, Pello Latasa, Jesus Castilla, Andrew Smith, Birgitta Henriques-Normark, Robert Whittaker, Lucia Pastore Celentano, Camelia Savulescu, (2018). Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: Implications for adult vaccination. Thorax doi: 10.1136/thoraxjnl-2018-211767
- Evelyn Balsells, Ron Dagan, Inci Yildirim, Prabhu P. Gounder, Anneke Steens, Carmen Muñoz-Almagro, Chiara Mameli, Rama Kandasamy, Noga Givon Lavi, Laura Daprai, Arie van der Ende, Krzysztof Trzciński, Susan A. Nzenze, Susan Meiring, Dona Foster, Lisa R. Bulkow, Karen Rudolph, Ana Valero-Rello, Struan Ducker, Didrik Frimann Vestrheim, Anne von Gottberg, Stephen I. Pelton, GianVincenzo Zuccotti, Andrew J. Pollard, Elisabeth A.M. Sanders, Harry Campbell, Shabir A. Madhi, Harish Nair, Moe H. Kyaw, (2018). The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis. Journal of Infection s. 368-378. doi: 10.1016/j.jinf.2018.06.004
- Berit Granum, Didrik Frimann Vestrheim, Ketil Størdal, Eyvind Ohm, Pål Suren, Linn Bøhler, Lars Christian Mørch Stene, Hans Henrik Blystad, (2018). Barn og unges fysiske helse.
- Ingerid Ørjansen Kirkeleite, Jon Bohlin, Lonneke Scheffer, Einar T. Weme, DIDRIK FRIMANN VESTRHEIM, (2018). Draft genome sequence of a potentially novel Streptococcus species belonging to the Streptococcus mitis group. Microbiology Resource Announcements (MRA) doi: 10.1128/genomeA.00620-18
- Øystein Rolandsen Riise, Ida Laake, DIDRIK FRIMANN VESTRHEIM, Brita Askeland Winje, Dag Moster, Jann Storsæter, (2018). Preterm Children Have Higher Risk Than Full-Term Children of Invasive Pneumococcal Disease During the First Two Years of Life. The Pediatric Infectious Disease Journal s. e195-e200. doi: 10.1097/INF.0000000000001989
- Alex-Mikael Barkoff, Jussi Mertsola, Denis Pierard, Tine Dalby, Silje Vermedal Høgh, Sophie Guillot, P Stefanelli, Marjolein van Gent, Guy Berbers, DIDRIK FRIMANN VESTRHEIM, Margrethe Greve-Isdahl, Lena Wehlin, Margaretha Ljungman, Norman K. Fry, Kevin Markey, Kari Auranen, Qiushui Hea, (2018). Surveillance of circulating bordetella pertussis strains in Europe during 1998 to 2015. Journal of Clinical Microbiology doi: 10.1128/JCM.01998-17
- Øystein Rolandsen Riise, Ida Laake, DIDRIK FRIMANN VESTRHEIM, Elmira Flem, Dag Moster, Marianne A Riise Bergsaker, Jann Storsæter, (2017). Risk of pertussis in relation to degree of prematurity in children less than 2 years of age. The Pediatric Infectious Disease Journal s. e151-e156. doi: 10.1097/INF.0000000000001545
- Hans-Christian Slotved, Carmen L. Sheppard, Trine Dalby, Arie van der Ende, Norman K. Fry, Eva Morfeldt, Outi Nyholm, Assaf Rokney, Merav Ron, Lotta Siira, Kevin J. Scott, Andrew Smith, Louise Thom, Maija Toropainen, DIDRIK FRIMANN VESTRHEIM, (2017). External Quality Assurance for Laboratory Identification and Capsular Typing of Streptococcus pneumoniae. Scientific Reports doi: 10.1038/s41598-017-13605-8
- Camelia Savulescu, Pavla Krizova, Agnes Lepoutre, Jolita Mereckiene, DIDRIK FRIMANN VESTRHEIM, Pilar Ciruela, Maria Ordobas, Marcela Guevara, Eisin McDonald, Eva Morfeldt, Jana Kozakova, Emmanuelle Varon, Suzanne Cotter, Brita Askeland Winje, Carmen Munoz-Almagro, Luis Garcia, Jesus Castilla, Andrew Smith, B Henriques-Normark, Lucia Pastore Celentano, Germaine Hanquet, (2017). Effect of high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children in SpIDnet countries: an observational multicentre study. The Lancet Respiratory Medicine s. 648-656. doi: 10.1016/S2213-2600(17)30110-8
- Hans Kristian Fløystad, Are Martin Holm, Leiv Sandvik, DIDRIK FRIMANN VESTRHEIM, Bjørn Jardar Brandsæter, Dag Berild, (2017). Increased long-term mortality after survival of invasive pneumococcal disease: a population-based study. Infectious Diseases s. 365-372. doi: 10.1080/23744235.2016.1271997
- DIDRIK FRIMANN VESTRHEIM, Richard White, Ingeborg Sundsvalen Aaberge, Audun Aase, (2016). Geographical differences in seroprevalence of Borrelia burgdorferi antibodies in Norway, 2011-2013. Ticks and Tick-borne Diseases s. 698-702. doi: 10.1016/j.ttbdis.2016.02.020
- Anneke Steens, Natacha Alexandra da Fonseca Milhano, Ingeborg Sundsvalen Aaberge, DIDRIK FRIMANN VESTRHEIM, (2016). In vitro and in vivo comparison of transport media for detecting nasopharyngeal carriage of Streptococcus pneumoniae. PeerJ doi: 10.7717/peerj.2449
- Emily MacDonald, DIDRIK FRIMANN VESTRHEIM, Richard White, Kirsten Konsmo, Heidi Lange, Audun Aase, Karin Maria Nygård, Pawel Stefanoff, Ingeborg Sundsvalen Aaberge, Line Vold, (2016). Are the current notification criteria for Lyme borreliosis in Norway suitable? Results of an evaluation of Lyme borreliosis surveillance in Norway, 1995-2013. BMC Public Health doi: 10.1186/s12889-016-3346-9
- Åsa Susanne Askim, Arne Mehl, Julie Paulsen, Andrew T. DeWan, DIDRIK FRIMANN VESTRHEIM, Bjørn Olav Åsvold, Jan Kristian Damås, Erik Solligård, (2016). Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993-2011: an observational study. BMC Infectious Diseases doi: 10.1186/s12879-016-1553-8
- DIDRIK FRIMANN VESTRHEIM, Heidi Lange, Karin Maria Nygård, Katrine Borgen, Astrid Lousie Wester, M L Kvarme, Line Vold, (2016). Are ready-to-eat salads ready to eat? An outbreak of Salmonella Coeln linked to imported, mixed, pre-washed and bagged salad, Norway, November 2013. Epidemiology and Infection s. 1756-1760. doi: 10.1017/S0950268815002769
- Anneke Steens, Dominique A Caugant, Ingeborg Sundsvalen Aaberge, DIDRIK FRIMANN VESTRHEIM, (2015). Decreased carriage and genetic shifts in the Streptococcus pneumoniae population after changing the seven-valent to the thirteen-valent pneumococcal vaccine in Norway. The Pediatric Infectious Disease Journal s. 875-883. doi: 10.1097/INF.0000000000000751
- Anneke Steens, DIDRIK FRIMANN VESTRHEIM, Birgitte Freiesleben De Blasio, (2015). Pneumococcal vaccination in older adults in the era of childhood vaccination: Public health insights from a Norwegian statistical prediction study. Epidemics s. 24-31. doi: 10.1016/j.epidem.2015.01.001
- M van Gent, CJ Heuvelman, HG van der Heide, HO Hallander, A Advani, N Guiso, CH Wirsing Von Konig, DIDRIK FRIMANN VESTRHEIM, T Dalby, NK Fry, D Pierard, L Detemmerman, J Zavadilova, K Fabianova, C Logan, A Habington, M Byrne, A Lutynska, E Mosiej, C Pelaz, K Gröndahl-Yli-Hannuksela, AM Barkoff, J Mertsola, A Economopoulou, Q He, FR Mooi, (2015). Analysis of Bordetella pertussis clinical isolates circulating in European countries during the period 1998–2012. European Journal of Clinical Microbiology and Infectious Diseases s. 821-830. doi: 10.1007/s10096-014-2297-2
- Hege Salvesen Blix, DIDRIK FRIMANN VESTRHEIM, Vidar Hjellvik, Dagfinn Skaare, Andreas Christensen, Martin Steinbakk, (2015). Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance?. Epidemiology and Infection s. 1884-1892. doi: 10.1017/S0950268814002908
- A Zeddeman, M van Gent, CJ Heuvelman, HG van der Heide, MJ Bart, A Advani, HO Hallander, CH Wirsing von Konig, M Riffelman, Jann Storsæter, DIDRIK FRIMANN VESTRHEIM, T Dalby, KA Krogfelt, NK Fry, AM Barkoff, J Mertsola, Q He, F Mooi, (2014). Investigations into the emergence of pertactin-deficient bordetella pertussis isolates in six European countries, 1996 to 2012. Eurosurveillance
- Cecilie Torp Andersen, Trude Margrete Arnesen, Caugant Dominique, Petter Elstrøm, Kjersti Wik Larssen, Gunnar Skov Simonsen, Dagfinn Skaare, Martin Steinbakk, Gaute Syversen, DIDRIK FRIMANN VESTRHEIM, Frode Width-Gran, (2014). HUMAN CLINICAL ISOLATES.
- Anneke Steens, DIDRIK FRIMANN VESTRHEIM, Ingeborg Sundsvalen Aaberge, Berit Sofie Wiklund, Jann Storsæter, Marianne A Riise Bergsaker, Karin Rønning, Ellen Furuseth, (2014). A review of the evidence to inform pneumococcal vaccine recommendations for risk groups aged 2 years and older. Epidemiology and Infection s. 2471-2482. doi: 10.1017/S0950268814001514
- Anneke Steens, Marianne A Riise Bergsaker, Ingeborg Sundsvalen Aaberge, Karin Rønning, DIDRIK FRIMANN VESTRHEIM, (2013). Prompt effect of replacing the 7-valent pneumococcal conjugate vaccine with the 13-valent vaccine on the epidemiology of invasive pneumococcal disease in Norway. Vaccine s. 6232-6238. doi: 10.1016/j.vaccine.2013.10.032
- Gunnar Skov Simonsen, Martin Steinbakk, Petter Elstrøm, Kjersti Wik Larssen, Frode Width Gran, DIDRIK FRIMANN VESTRHEIM, Andreas Radtke, Karin Rønning, Cecilie Torp Andersen, Susanne Gjeruldsen Dudman, Olav Hungnes, (2013). Human Clinical Isolates. s. 57-85.
- DIDRIK FRIMANN VESTRHEIM, Martin Steinbakk, Martha Langedok Bjørnstad, A. Moghaddam, N. Reinton, Mette Lundstrøm Dahl, Nils Grude, Per Sandven, (2012). Recovery of Bordetella pertussis from PCR-Positive Nasopharyngeal Samples Is Dependent on Bacterial Load. Journal of Clinical Microbiology s. 4114-4115. doi: 10.1128/JCM.01553-12
- DIDRIK FRIMANN VESTRHEIM, Martin Steinbakk, Ingeborg Sundsvalen Aaberge, Dominique A Caugant, (2012). Postvaccination Increase in Serotype 19A Pneumococcal Disease in Norway Is Driven by Expansion of Penicillin-Susceptible Strains of the ST199 Complex. Clinical and Vaccine Immunology s. 443-445. doi: 10.1128/CVI.05563-11
- Hans Henrik Blystad, Gabriel Ånestad, DIDRIK FRIMANN VESTRHEIM, Steinar Madsen, Karin Rønning, (2012). Increased incidence of Mycoplasma pneumoniae infection in Norway 2011. Eurosurveillance s. 12-14.
- Maria Christine Magnus, DIDRIK FRIMANN VESTRHEIM, Wenche Nystad, Siri Eldevik Håberg, Hein Stigum, Stephanie J. London, Marianne A Riise Bergsaker, Dominique A Caugant, Ingeborg Sundsvalen Aaberge, Per Nafstad, (2012). Decline in early childhood respiratory tract infections in the Norwegian Mother and Child Cohort Study after introduction of pneumococcal conjugate vaccination. The Pediatric Infectious Disease Journal s. 951-955. doi: 10.1097/INF.0b013e31825d2f76
- Didrik Frimann Vestrheim, Peter Gaustad, Ingeborg Sundsvalen Aaberge, Dominique A Caugant, (2011). Pherotypes of pneumococcal strains co-existing in healthy children. Infection, Genetics and Evolution s. 1703-1708. doi: 10.1016/j.meegid.2011.07.003
- Magnus Unemo, D Golparian, Gaute Syversen, Didrik Frimann Vestrheim, Harald Moi, (2010). Two cases of verified clinical failures using internationally recommended first-line cefixime for gonorrhoea treatment, Norway, 2010. Eurosurveillance s. 9-11.
- Didrik Frimann Vestrheim, Ernst Arne Høiby, Marianne A Riise Bergsaker, Karin Rønning, Ingeborg Sundsvalen Aaberge, Dominique A Caugant, (2010). Indirect effect of conjugate pneumococcal vaccination in a 2+1 dose schedule. Vaccine s. 2214-2221. doi: 10.1016/j.vaccine.2009.12.054
- Didrik Frimann Vestrheim, Ernst Arne Høiby, Ingeborg Sundsvalen Aaberge, Dominique A Caugant, (2010). Impact of a pneumococcal conjugate vaccination program on carriage among children in Norway. Clinical and Vaccine Immunology s. 325-334. doi: 10.1128/CVI.00435-09
- Ernst Arne Høiby, Didrik Frimann Vestrheim, Dominique A Caugant, Karianne Wiger Gammelsrud, (2008). Bakteriell resistens mot antibiotika. Tidsskrift for Den norske legeforening s. 2452-2456.
- Didrik Frimann Vestrheim, Ernst Arne Høiby, Ingeborg Aase S. Aaberge, Dominique A Caugant, (2008). Phenotypic and genotypic characterization of Streptococcus pneumoniae strains colonizing children attending day-care centers in Norway. Journal of Clinical Microbiology s. 2508-2518. doi: 10.1128/JCM.02296-07
- Didrik Frimann Vestrheim, Øistein Løvoll, Ingeborg Aase S. Aaberge, Dominique A Caugant, Ernst Arne Høiby, Hilde Synøve Waleur Bakke, Marianne A Riise Bergsaker, (2008). Effectiveness of a 2+1 dose schedule pneumococcal conjugate vaccination programme on invasive pneumococcal disease among children in Norway. Vaccine s. 3277-3281. doi: 10.1016/j.vaccine.2008.03.087
Rapporter og bøker
- Brita Askeland Winje, Jacob Dag Berild, Didrik Frimann Vestrheim, Eva Marie-Louise Denison, Tiia Lepp, Adam Roth, Jann Storsæter, Palle Valentiner-Branth, Hans-Christian Slotved, (2019). Efficacy and effectiveness of pneumococcal vaccination in elderly – an update of the literature
- Cecilie Torp Andersen, Gunnar Skov Simonsen, Trude Margrete Arnesen, Anne Margrete Urdahl, Elisabeth Astrup, Hege Salvesen Blix, Dominique A Caugant, Kari Grave, Kjersti Wik Larssen, Madelaine Norström, Andreas Radtke, Jannice Schau Slettemeås, Dagfinn Skaare, Martin Steinbakk, Gaute Syversen, DIDRIK FRIMANN VESTRHEIM, Astrid Lousie Wester, Frode Width-Gran, (2015). NORM/NORM-VET 2014. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway.
- Hans Henrik Blystad, Dominique A Caugant, Inger Lise Haugen, Kirsten Konsmo, Anneke Steens, Martin Steinbakk, Jann Storsæter, DIDRIK FRIMANN VESTRHEIM, (2014). Årsrapport for 2013. Invasive infeksjoner
- Hans Henrik Blystad, Dominique A Caugant, Inger Lise Haugen, Kirsten Konsmo, Anneke Steens, Martin Steinbakk, Jann Storsæter, DIDRIK FRIMANN VESTRHEIM, (2013). Årsrapport for 2012. Invasive infeksjoner
- Didrik Frimann Vestrheim, (2012). Impact of childhood immunisation with a pneumococcal conjugate vaccine in Norway
- Hans Henrik Blystad, Dominique A Caugant, Inger Lise Haugen, Karin Rønning, Anneke Steens, Martin Steinbakk, DIDRIK FRIMANN VESTRHEIM, Berit Sofie Wiklund, (2012). Årsrapport 2011 for sykdomsprogrammet: Invasive infeksjoner
- Marianne A Riise Bergsaker, Berit Feiring, Maria Elisabeth Hagerup-Jenssen, Elmira Flem, Audun Aase, Trude Arnesen, Inger Lise Haugen, Jeanette Stålcrantz, Anne-Marthe Indregard, Berit Sofie Wiklund, Silje Bruland Lavoll, DIDRIK FRIMANN VESTRHEIM, Ingeborg Sundsvalen Aaberge, M Kirsti Vainio, (2012). Barnevaksinasjonsprogrammet i Norge. Rapport for 2011
Andre
- Dag Berild, Anneke Steens, Brita Askeland Winje, Tor Erik Danielsen, Jan Håkon Fjeldheim, Helene Daae-Qvale Holmemo, Didrik Frimann Vestrheim, (2019). Management and control of an outbreak of vaccine-preventable severe pneumococcal disease at a shipyard in Norway. Journal of Infection doi: 10.1016/j.jinf.2019.12.015
- DIDRIK FRIMANN VESTRHEIM, Britt Wolden, (2017). HPV-vaksinene gir god beskyttelse. Tidsskrift for Den norske legeforening s. 979-980. doi: 10.4045/tidsskr.17.0585
- Emily MacDonald, Trude Arnesen, Arne Brantsæter, Per Gerlyng, Meera Grepp, Bjørn Åsheim Hansen, Knut Jønsrud, B. Lundgren, Hilde Mellegård, Janne Møller-Stray, Karin Rønning, Didrik Frimann Vestrheim, Line Vold, (2013). Outbreak of wound botulism in people who inject drugs, Norway, October to November 2013. Eurosurveillance s. 2-5.
- Usha Hartgill, irena jakopanec, DIDRIK FRIMANN VESTRHEIM, (2011). Gonoré - på tide med nye retningslinjer. Tidsskrift for Den norske legeforening s. 671-672. doi: 10.4045/tidsskr.10.1380
- Harald Moi, DIDRIK FRIMANN VESTRHEIM, Anna Olaug Olsen, (2011). Reduser bruken av azitromycin som engangsdose673–4. Tidsskrift for Den norske legeforening s. 673-674.
- DIDRIK FRIMANN VESTRHEIM, Ernst Arne Høiby, Ingeborg Sundsvalen Aaberge, Marianne A Riise Bergsaker, Karin Rønning, Dominique A Caugant, (2010). Population-wide effects of PCV7 in a 2+1 dose schedule vaccination programme.