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  • Maternal anxiety/depression and diet in pregnancy and child outcomes: Gene haplotype associations in parent-child-trios

Project

Maternal anxiety/depression and diet in pregnancy and child outcomes: Gene haplotype associations in parent-child-trios - project description

Published

The purpose of this project is to investigate the relationship between genetic variants, environmental exposure in pregnancy and psychological difficulties in children.


Summary

The purpose of this project is to investigate the relationship between genetic variants, environmental exposure in pregnancy and psychological difficulties in children, using data from the Norwegian Mother and Child study and genetic association analyses.

We want to look at relationships where the child has a psychological problem (eg: ADHD, behavioural difficulties and emotional difficulties).

The purpose is to investigate the child's genetic markers (which increase the risk of disease in the child) and genes in maternity (maternal genes) that increase the risk of the child through pregnancy. We investigate whether maternal exposure directly affects the risk of the child, along with genetic effects. Perhaps there is an interaction between exposure and genetic effects, i.e. whether genetic effects change depending on whether the mother is exposed or not.

Collaborating institutions

  • Norwegian Institute of Public Health 
  • University of Bergen

Project leader 

Project number

2401

Start

2018

Status

Active

Approvals

Regional Committees for Medical and Health Research Ethics (REC)

Project owner/ Project manager

University of Oslo