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CeFH Genetic Friday: Genetically informed designs for causal inference in child and adolescent mental health research

Presentation by Jean-Baptiste Pingault, University College London

Presentation by Jean-Baptiste Pingault, University College London

Presentation by Jean-Baptiste Pingault, University College London

About Genetics Fridays

Genetics Fridays are held every Friday at the Centre of Fertility and Health. This is an informal venue for all employees at the Norwegian Institute of Public Health and collaborators who are working with genetics, planning to implement genetics in their work, or merely have an interest in genetics. There is room for presentations and/or discussions, where participants can share knowledge and experience, come up with ideas and discuss projects and methods. The big meeting room at the centre (room 201) is reserved every Friday from 13.00-14.00, available for meetings or discussions. Some Fridays there will be presentations on selected topics, methods or projects. These presentations will be announced in our event calendar. We make waffles for everyone at 12.30!

Contact Kristine Løkås Jacobsen if you have ideas on interesting topics we can address, or if you want to present something yourself.

05. Apr 2019 - 13:00-14:00 | Seminar
Marcus Thranes gate 2, meeting room 2nd floor

About the speaker

Jean-Baptiste Pingault is a Lecturer at the Department of Clinical, Educational and Health Psychology (CEPH), University College London (UCL), as well as a visiting researcher at the Social, Genetic, and Developmental Psychiatry centre, King’s College London (KCL).

About the presentation

Mental health is responsible for a substantial part of the burden of disease – up to 32% of years lived with disability. Mental health research – especially in young people – remains a high need-low investment area (Medical Research Foundation). Within the field of mental health research “We need to understand causes to better inform prevention” as highlighted in a British Medical Journal's editorial (2018) on young people's mental health. Accordingly, my research focuses on identifying causal risk factors for children's and adolescents' mental health. Recently, I published a Nature Review Genetics article on genetically informed methods for causal inference, arguing that genetics can help us to strengthen causal inference. I will present some of our published and current empirical research implementing such methods. In particular, I will present findings from the twin differences design and from polygenic score approaches to clarify the aetiology of a range of outcomes including ADHD symptoms, substance use, and bullying victimization.