Effects of dioxins and DL-PCBs on semen quality – basis for the new, lower tolerable weekly intake set by the European Food Safety Authority (EFSA).
Helle Katrine Knutsen is toxicologist and scientist at the Norwegian Institute of Public Health (Department of Environmental Exposure and Epidemiology). She has a master in cell biology (UiO), and graduated in 1995 from the Institute of Medical Biochemistry (UiO) on a project on gene regulation in rat Sertoli cells. After a post.doc period at the same institute, she started at NIPH in 1999. Here she soon became involved in exposure to environmental toxicants, biomarkers of exposure and association with health outcomes in MoBa. Helle also engaged in health risk assessments in both VKM and EFSA, and is presently member of EFSA’s Nutrition Panel and chair of VKM’s panel on contaminants in the food chain. Before that she was member of EFSA’s Panel on Contaminants (CONTAM) for nine years (Panel Chair for three years), and was heavily involved in the risk assessment on dioxins and DL-PCBs.
Helle will present the risk assessment on dioxins and DL-PCBs, with emphasis on the experimental animal and epidemiological data linking exposure to dioxins and DL-PCBs to reduction is semen quality. Even though the exposure has declined more than 80% the last decades, the current exposure in Norway is higher than the new tolerable weekly intake. This may be relevant to address further in MoBa.