Prosjekt
Reliability of Free and Total BPA analyte measures in MoBa - prosjektbeskrivelse
Publisert
We propose a reliability study of BPA biomarkers over the course of pregnancy that separates total and free BPA, using the reliability substudy urine samples collected in MoBa.
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Start
01.08.2011
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Slutt
31.12.2014
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Status
Avsluttet
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Godkjenninger
Regional committees for medical and health research ethics
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Prosjekteier/ prosjektansvarlig
Norwegian Institute of Public Health
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Tilknyttet studie
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Prosjektleder
Sammendrag
BBPA is rapidly metabolized. Therefore in the absence of a constant exposure source and intensity, biomarker levels would be expected to change over time, as has previously been reported. Only free (unconjugated) BPA exhibits endocrine activity*** however, in general, existing epidemiological studies have measured total BPA (the sum of free and conjugated) biomarkers. Total BPA biomarker concentration may further be impacted by contamination with environmental sources of free BPA, or in the biospecimen collection process or materials. We propose a reliability study of BPA biomarkers over the course of pregnancy that separates total and free BPA, using the reliability substudy urine samples collected in MoBa.Se fullstendig prosjektbeskrivelse på Cristin for mer informasjon om resultater, deltakere, kontakter med mer
Prosjektdeltakere
Prosjektleder
Heidi Aase, Norwegian Institute of Public Health